PMID- 16777467 OWN - NLM STAT- MEDLINE DCOM- 20070511 LR - 20220410 IS - 1532-2769 (Electronic) IS - 1356-689X (Linking) VI - 12 IP - 2 DP - 2007 May TI - The initial effects of knee joint mobilization on osteoarthritic hyperalgesia. PG - 109-18 AB - Physiotherapists often employ lower limb joint mobilization to reduce pain and increase function. However, there is little experimental data confirming its efficacy. The purpose of this study was to investigate the initial effects of accessory knee joint mobilization on measures of pain and function in individuals with knee osteoarthritis. The study employed a double-blind, controlled, within-subjects repeated-measures design. Thirty-eight subjects with mild to moderate knee pain participated. The effects of a 9-min, non-noxious, AP mobilization of the tibio-femoral joint were compared with manual contact and no-contact interventions. Pressure pain threshold (PPT) and 3-m 'up and go' time were measured immediately before and after each intervention. Results demonstrated a significantly greater mean (95% CI) percentage increase in PPT following knee joint mobilization (27.3% (20.9-33.7)) than after manual contact (6.4% (0.4-12.4)) or no-contact (-9.6% (-20.7 to 1.6)) interventions. Knee joint mobilization also increased PPT at a distal, non-painful site and reduced 'up and go' time significantly more (-5% (-9.3 to 0.8)) than manual contact (-0.4% (-4.2 to 3.5)) or no-contact control (+7.9% (2.6-13.2)) interventions. This study therefore provides new experimental evidence that accessory mobilization of an osteoarthritic knee joint immediately produces both local and widespread hypoalgesic effects. It may therefore be an effective means of reducing pain in this population. FAU - Moss, Penny AU - Moss P AD - School of Physiotherapy, Curtin University of Technology, GPO Box U1987, Perth, WA, Australia. FAU - Sluka, Kathleen AU - Sluka K FAU - Wright, Anthony AU - Wright A LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20060613 PL - Scotland TA - Man Ther JT - Manual therapy JID - 9610924 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Analysis of Variance MH - Double-Blind Method MH - Female MH - Follow-Up Studies MH - Humans MH - Hyperalgesia/diagnosis/*therapy MH - Male MH - Manipulation, Orthopedic/*methods MH - Middle Aged MH - Osteoarthritis, Knee/diagnosis/*therapy MH - Pain Measurement MH - Physical Therapy Modalities MH - Probability MH - Range of Motion, Articular/*physiology MH - Recovery of Function MH - Reference Values MH - Risk Factors MH - Severity of Illness Index MH - Treatment Outcome EDAT- 2006/06/17 09:00 MHDA- 2007/05/12 09:00 CRDT- 2006/06/17 09:00 PHST- 2004/09/22 00:00 [received] PHST- 2006/01/25 00:00 [revised] PHST- 2006/02/15 00:00 [accepted] PHST- 2006/06/17 09:00 [pubmed] PHST- 2007/05/12 09:00 [medline] PHST- 2006/06/17 09:00 [entrez] AID - S1356-689X(06)00040-3 [pii] AID - 10.1016/j.math.2006.02.009 [doi] PST - ppublish SO - Man Ther. 2007 May;12(2):109-18. doi: 10.1016/j.math.2006.02.009. Epub 2006 Jun 13.