PMID- 16781155
OWN - NLM
STAT- MEDLINE
DCOM- 20060926
LR  - 20081121
IS  - 0966-842X (Print)
IS  - 0966-842X (Linking)
VI  - 14
IP  - 8
DP  - 2006 Aug
TI  - Interaction of foot-and-mouth disease virus with dendritic cells.
PG  - 346-7
AB  - Despite several decades of investigation, the manner in which foot-and-mouth 
      disease virus (FMDV) interacts with the innate and adaptive immune compartments 
      is not completely understood. The importance of elucidating this relationship is 
      emphasized by the inability of current FMDV vaccines to provide long-term 
      protection and the recent outbreaks of FMDV in formerly disease-free countries. 
      Dendritic cells (DCs) are professional antigen-presenting cells that have evolved 
      to monitor the environment and provide a link between the innate and adaptive 
      immune systems. Comprehending the cross-talk between DC and FMDV will provide 
      valuable information towards understanding the host response to the virus and 
      will aid in the design of effective tools and vaccines to block virus spread.
FAU - Bayry, Jagadeesh
AU  - Bayry J
AD  - The Edward Jenner Institute for Vaccine Research, University of Oxford, Compton, 
      Newbury, Berkshire RG20 7NN, UK. jagadeesh.bayry@umrs681.jussieu.fr
FAU - Tough, David F
AU  - Tough DF
LA  - eng
PT  - Letter
DEP - 20060615
PL  - England
TA  - Trends Microbiol
JT  - Trends in microbiology
JID - 9310916
SB  - IM
MH  - Animals
MH  - Dendritic Cells/immunology/*virology
MH  - Foot-and-Mouth Disease/immunology/*virology
MH  - Foot-and-Mouth Disease Virus/*growth & development
MH  - Immunity, Innate/immunology
EDAT- 2006/06/20 09:00
MHDA- 2006/09/27 09:00
CRDT- 2006/06/20 09:00
PHST- 2006/01/27 00:00 [received]
PHST- 2006/04/19 00:00 [revised]
PHST- 2006/06/01 00:00 [accepted]
PHST- 2006/06/20 09:00 [pubmed]
PHST- 2006/09/27 09:00 [medline]
PHST- 2006/06/20 09:00 [entrez]
AID - S0966-842X(06)00131-4 [pii]
AID - 10.1016/j.tim.2006.06.001 [doi]
PST - ppublish
SO  - Trends Microbiol. 2006 Aug;14(8):346-7. doi: 10.1016/j.tim.2006.06.001. Epub 2006 
      Jun 15.