PMID- 16788526 OWN - NLM STAT- MEDLINE DCOM- 20060912 LR - 20191026 IS - 0761-8425 (Print) IS - 0761-8425 (Linking) VI - 23 IP - 3 Pt 1 DP - 2006 Jun TI - [Economic analysis of home based versus hospital outpatient chemotherapy in stage IV non small cell lung cancer]. PG - 255-63 AB - BACKGROUND: French law and government decisions have induced new development for home base treatments. The objective was to compare cost of home base chemotherapy (HBC) versus outpatient infusions, for non small cell lung cancer (NSCLC). METHODS: 10 patients were selected in each category. D8 of their cycles was performed at home compared to outpatient infusion. Costs were based on national fees with cytostatic drugs as supplement. The real cost was also assessed through a specific questionnaire. RESULTS: 30 D8 infusions were carried out at hospital and 24 D8 infusions at home. Average cost by cycle was 2,829.51 euros [2 560.74-3 147.02] for hospital infusion, 2,372.50 euros [1 962.75-2 792.88] for HBC (-16.15%). Difference was -457.01 euros by cycle [-919.74; 26.82]. Real costs by injection for BHC was 484.42 euros [424.18; 540.32] versus a fee of 699.89 euros [643.64; 750.23]. There were no difference in terms of adverse events. CONCLUSION: HBC for NSCLC is feasible. Average costs by cycle is lower of 16% versus hospital infusion. The results of this non randomized study had to be confirm by further clinical trials. FAU - Vergnenegre, A AU - Vergnenegre A AD - Service de l'Information Medicale et de l'Evaluation, Hopital du Cluzeau, CHU de Limoges, France. alain.vergnenegre@unilim.fr FAU - Decroisette, C AU - Decroisette C FAU - Vincent, F AU - Vincent F FAU - Dalmay, F AU - Dalmay F FAU - Melloni, B AU - Melloni B FAU - Bonnaud, F AU - Bonnaud F FAU - Eichler, B AU - Eichler B LA - fre PT - Comparative Study PT - English Abstract PT - Journal Article TT - Analyse economique de l'administration d'une chimiotherapie en hospitalisation a domicile (HAD) comparee a l'hospitalisation de jour dans les cancers bronchopulmonaires non a petites cellules de stade IV. PL - France TA - Rev Mal Respir JT - Revue des maladies respiratoires JID - 8408032 SB - IM CIN - Rev Mal Respir. 2006 Jun;23(3 Pt 1):207-8. PMID: 16788519 MH - Ambulatory Care/economics MH - Antineoplastic Combined Chemotherapy Protocols/*economics/*therapeutic use MH - Carcinoma, Non-Small-Cell Lung/*drug therapy/pathology MH - France MH - Home Care Services/*economics MH - Humans MH - Infusions, Intravenous MH - Lung Neoplasms/*drug therapy/pathology MH - Middle Aged EDAT- 2006/06/22 09:00 MHDA- 2006/09/13 09:00 CRDT- 2006/06/22 09:00 PHST- 2006/06/22 09:00 [pubmed] PHST- 2006/09/13 09:00 [medline] PHST- 2006/06/22 09:00 [entrez] AID - MDOI-RMR-06-2006-23-3-0761-8425-101019-200518635 [pii] AID - 10.1016/s0761-8425(06)71575-3 [doi] PST - ppublish SO - Rev Mal Respir. 2006 Jun;23(3 Pt 1):255-63. doi: 10.1016/s0761-8425(06)71575-3.