PMID- 16793610
OWN - NLM
STAT- MEDLINE
DCOM- 20080430
LR  - 20060623
IS  - 1673-4254 (Print)
IS  - 1673-4254 (Linking)
VI  - 26
IP  - 6
DP  - 2006 Jun
TI  - [Oncogene ZNF217 amplification on chromosome 20 q in ovarian serous 
      cystadenocarcinoma and its clinical implications].
PG  - 824-5
AB  - OBJECTIVE: To investigate the amplification of zinc finger protein 217 (ZNF217) 
      gene on chromosome 20 in ovarian cancer and its clinical significance. METHODS: 
      Twenty-three specimens of ovarian carcinoma (11 cases of early stage and 12 
      advanced stage), 10 specimens of benign ovarian tumors and 7 normal ovaries were 
      examined for ZNF217 gene amplification on chromosome 20 by fluorescence in situ 
      hybridization (FISH). RESULTS: ZNF217 gene amplification was detected in 12 cases 
      of ovarian cancer (52.17%) and 1 case of benign ovarian tumor, but not in normal 
      ovary. ZNF217 amplification was significantly associated with ovarian cancer. 
      CONCLUSION: Oncogene ZNF217 is associated with the tumor stage and poor prognosis 
      of patients with ovarian cancer.
FAU - Li, Jing
AU  - Li J
AD  - Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical 
      University, Guangzhou 510515, China. lijing7405@126.com
FAU - Zhong, Mei
AU  - Zhong M
FAU - Song, Lan-lin
AU  - Song LL
FAU - Su, Gui-dong
AU  - Su GD
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Nan Fang Yi Ke Da Xue Xue Bao
JT  - Nan fang yi ke da xue xue bao = Journal of Southern Medical University
JID - 101266132
RN  - 0 (Trans-Activators)
RN  - 0 (ZNF217 protein, human)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Chromosomes, Human, Pair 20/*genetics
MH  - Cystadenocarcinoma, Serous/*genetics/pathology
MH  - Female
MH  - *Gene Amplification
MH  - Gene Expression Regulation, Neoplastic
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Middle Aged
MH  - Ovarian Neoplasms/*genetics/pathology
MH  - Prognosis
MH  - Trans-Activators/*genetics
EDAT- 2006/06/24 09:00
MHDA- 2008/05/01 09:00
CRDT- 2006/06/24 09:00
PHST- 2006/06/24 09:00 [pubmed]
PHST- 2008/05/01 09:00 [medline]
PHST- 2006/06/24 09:00 [entrez]
PST - ppublish
SO  - Nan Fang Yi Ke Da Xue Xue Bao. 2006 Jun;26(6):824-5.