PMID- 16796455
OWN - NLM
STAT- MEDLINE
DCOM- 20061130
LR  - 20060626
IS  - 1092-6429 (Print)
IS  - 1092-6429 (Linking)
VI  - 16
IP  - 3
DP  - 2006 Jun
TI  - Laparoscopic management of insulinoma in a child with multiple endocrine 
      neoplasia type 1.
PG  - 335-8
AB  - The diagnosis and surgical management of insulinomas associated with multiple 
      endocrine neoplasia type 1 (MEN1) pose additional problems in children because of 
      the long-term risk of recurrence of other pancreatic and non-pancreatic tumors. 
      We report a diagnostic confirmation by laparoscopic ultrasound of an insulinoma 
      and its successful removal by laparoscopic enucleation in an 8- year-old boy who 
      was admitted to our hospital with a history of recurrent episodes of absences, 
      headache, and visual and auditive disturbances diagnosed as 
      hyperinsulinism-related hypoglycemia. Magnetic resonance imaging of the pancreas 
      showed a small contrast-enhancing lesion in the body of the pancreas, suspected 
      for insulinoma. MEN1 was genetically proven by direct DNA testing. A pancreatic 
      tumor can arise before the age of 10 in patients with MEN1 and can be surgically 
      treated by a laparoscopical approach.
FAU - de Vogelaere, Kristel
AU  - de Vogelaere K
AD  - Department of Surgery, Vrije Universiteit Brussel, Brussels, Belgium. 
      hlkdvek@az.vub.ac.be
FAU - De Schepper, Jean
AU  - De Schepper J
FAU - Vanhoeij, Marjan
AU  - Vanhoeij M
FAU - De Mey, Johan
AU  - De Mey J
FAU - Goossens, Anita
AU  - Goossens A
FAU - Vanbesien, Jesse
AU  - Vanbesien J
FAU - De Backer, Antoine
AU  - De Backer A
FAU - Delvaux, Georges
AU  - Delvaux G
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Laparoendosc Adv Surg Tech A
JT  - Journal of laparoendoscopic & advanced surgical techniques. Part A
JID - 9706293
SB  - IM
MH  - Child
MH  - Diagnostic Imaging
MH  - Humans
MH  - Insulinoma/*pathology/*surgery
MH  - Laparoscopy/*methods
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Multiple Endocrine Neoplasia Type 1/*pathology
MH  - Pancreatic Neoplasms/*pathology/*surgery
EDAT- 2006/06/27 09:00
MHDA- 2006/12/09 09:00
CRDT- 2006/06/27 09:00
PHST- 2006/06/27 09:00 [pubmed]
PHST- 2006/12/09 09:00 [medline]
PHST- 2006/06/27 09:00 [entrez]
AID - 10.1089/lap.2006.16.335 [doi]
PST - ppublish
SO  - J Laparoendosc Adv Surg Tech A. 2006 Jun;16(3):335-8. doi: 
      10.1089/lap.2006.16.335.