PMID- 16797755
OWN - NLM
STAT- MEDLINE
DCOM- 20070116
LR  - 20220408
IS  - 0167-8140 (Print)
IS  - 0167-8140 (Linking)
VI  - 79
IP  - 3
DP  - 2006 Jun
TI  - Involved-node radiotherapy (INRT) in patients with early Hodgkin lymphoma: 
      concepts and guidelines.
PG  - 270-7
AB  - BACKGROUND AND PURPOSE: To describe new concepts for radiation fields in patients 
      with early stage Hodgkin lymphoma treated with a combined modality. PATIENTS AND 
      MATERIALS: Patients receiving combined modality therapy with at least 2 or 3 
      cycles of chemotherapy prior to radiotherapy. Pre- and postchemotherapy cervical 
      and thoracic CT scans are mandatory and should be performed, whenever possible, 
      in the treatment position with the use of image fusion capabilities. A 
      pre-chemotherapy PET scan is strongly recommended to increase the detection of 
      involved lymph nodes. RESULTS: Radiation fields are designed to irradiate the 
      initially involved lymph nodes exclusively and to encompass their initial volume. 
      In some cases, radiation fields are slightly modified to avoid unnecessary 
      irradiation of muscles or organs at risk. CONCLUSIONS: The concept of 
      involved-node radiotherapy (INRT) described here is the first attempt to reduce 
      the size of radiation fields compared to the classic involved fields used in 
      adult patients. Proper implementation of INRT requires adequate training and an 
      efficient prospective or early retrospective quality assurance program.
FAU - Girinsky, Theodore
AU  - Girinsky T
AD  - Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France. 
      girinsky@igr.fr
FAU - van der Maazen, Richard
AU  - van der Maazen R
FAU - Specht, Lena
AU  - Specht L
FAU - Aleman, Berthe
AU  - Aleman B
FAU - Poortmans, Philip
AU  - Poortmans P
FAU - Lievens, Yolande
AU  - Lievens Y
FAU - Meijnders, Paul
AU  - Meijnders P
FAU - Ghalibafian, Mithra
AU  - Ghalibafian M
FAU - Meerwaldt, Jacobus
AU  - Meerwaldt J
FAU - Noordijk, Evert
AU  - Noordijk E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20060622
PL  - Ireland
TA  - Radiother Oncol
JT  - Radiotherapy and oncology : journal of the European Society for Therapeutic 
      Radiology and Oncology
JID - 8407192
SB  - IM
CIN - Radiother Oncol. 2007 Jan;82(1):108-9; author reply 109-10. PMID: 17125861
MH  - Combined Modality Therapy
MH  - Dose-Response Relationship, Radiation
MH  - Europe
MH  - Hodgkin Disease/*radiotherapy
MH  - Humans
MH  - Lymph Nodes/diagnostic imaging/*pathology
MH  - *Practice Guidelines as Topic
MH  - Radiography
MH  - Radiotherapy, Conformal/methods/*standards
EDAT- 2006/06/27 09:00
MHDA- 2007/01/17 09:00
CRDT- 2006/06/27 09:00
PHST- 2006/04/28 00:00 [received]
PHST- 2006/05/18 00:00 [accepted]
PHST- 2006/06/27 09:00 [pubmed]
PHST- 2007/01/17 09:00 [medline]
PHST- 2006/06/27 09:00 [entrez]
AID - S0167-8140(06)00204-0 [pii]
AID - 10.1016/j.radonc.2006.05.015 [doi]
PST - ppublish
SO  - Radiother Oncol. 2006 Jun;79(3):270-7. doi: 10.1016/j.radonc.2006.05.015. Epub 
      2006 Jun 22.