PMID- 16807204 OWN - NLM STAT- MEDLINE DCOM- 20061212 LR - 20191210 IS - 0265-203X (Print) IS - 0265-203X (Linking) VI - 23 IP - 8 DP - 2006 Aug TI - Relationship between physicochemical properties and maximum residue levels and tolerances of crop-protection products for crops set by the USA, European Union and Codex. PG - 764-76 AB - Residues on foodstuffs resulting from the use of crop-protection products are a function of many factors, e.g. environmental conditions, dissipation and application rate, some of which are linked to the physicochemical properties of the active ingredients. Residue limits (maximum residue levels (MRLs) and tolerances) of fungicides, herbicides and insecticides set by different regulatory authorities are compared, and the relationship between physicochemical properties of the active ingredients and residue limits are explored. This was carried out using simple summary statistics and artificial neural networks. US tolerances tended to be higher than European Union MRLs. Generally, fungicides had the highest residue limits followed by insecticides and herbicides. Physicochemical properties (e.g. aromatic proportion, non-carbon proportion and water solubility) and crop type explained up to 50% of the variation in residue limits. This suggests that physicochemical properties of the active ingredients may control important aspects of the processes leading to residues. FAU - Thorbek, P AU - Thorbek P AD - Syngenta, Bracknell, RG42 6EY, UK. pernille.thorbek@syngenta.com FAU - Hyder, K AU - Hyder K LA - eng PT - Journal Article PL - England TA - Food Addit Contam JT - Food additives and contaminants JID - 8500474 RN - 0 (Fungicides, Industrial) RN - 0 (Herbicides) RN - 0 (Insecticides) RN - 0 (Pesticide Residues) SB - IM MH - Crops, Agricultural/chemistry MH - Databases, Factual MH - Drug Industry MH - Environmental Exposure/adverse effects MH - European Union MH - Food Contamination/analysis MH - Fungicides, Industrial/chemistry MH - Herbicides/chemistry MH - Insecticides/chemistry MH - Maximum Allowable Concentration MH - Neural Networks, Computer MH - Pesticide Residues/*chemistry/standards MH - United States MH - United States Environmental Protection Agency EDAT- 2006/06/30 09:00 MHDA- 2006/12/13 09:00 CRDT- 2006/06/30 09:00 PHST- 2006/06/30 09:00 [pubmed] PHST- 2006/12/13 09:00 [medline] PHST- 2006/06/30 09:00 [entrez] AID - L6238231P01N82X5 [pii] AID - 10.1080/02652030600643377 [doi] PST - ppublish SO - Food Addit Contam. 2006 Aug;23(8):764-76. doi: 10.1080/02652030600643377.