PMID- 16808068
OWN - NLM
STAT- MEDLINE
DCOM- 20060727
LR  - 20191210
IS  - 0954-4119 (Print)
IS  - 0954-4119 (Linking)
VI  - 220
IP  - 4
DP  - 2006 May
TI  - Selective laser sintering of hydroxyapatite reinforced polyethylene composites 
      for bioactive implants and tissue scaffold development.
PG  - 521-31
AB  - Selective laser sintering (SLS) has been investigated for the production of 
      bioactive implants and tissue scaffolds using composites of high-density 
      polyethylene (HDPE) reinforced with hydroxyapatite (HA) with the aim of achieving 
      the rapid manufacturing of customized implants. Single-layer and multilayer block 
      specimens made of HA-HDPE composites with 30 and 40 vol % HA were sintered 
      successfully using a CO2 laser sintering system. Laser power and scanning speed 
      had a significant effect on the sintering behaviour. The degree of particle 
      fusion and porosity were influenced by the laser processing parameters, hence 
      control can be attained by varying these parameters. Moreover, the SLS processing 
      allowed exposure of HA particles on the surface of the composites and thereby 
      should provide bioactive products. Pores existed in the SLS-fabricated composite 
      parts and at certain processing parameters a significant fraction of the pores 
      were within the optimal sizes for tissue regeneration. The results indicate that 
      the SLS technique has the potential not only to fabricate HA-HDPE composite 
      products but also to produce appropriate features for their application as 
      bioactive implants and tissue scaffolds.
FAU - Hao, L
AU  - Hao L
AD  - Rapid Manufacturing Research Group, Wolfson School of Mechanical and 
      Manufacturing Engineering, Loughborough University, Loughborough, Leicestershire, 
      UK. l.hao@lboro.ac.uk
FAU - Savalani, M M
AU  - Savalani MM
FAU - Zhang, Y
AU  - Zhang Y
FAU - Tanner, K E
AU  - Tanner KE
FAU - Harris, R A
AU  - Harris RA
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Proc Inst Mech Eng H
JT  - Proceedings of the Institution of Mechanical Engineers. Part H, Journal of 
      engineering in medicine
JID - 8908934
RN  - 0 (Biocompatible Materials)
RN  - 0 (Polyethylenes)
RN  - 91D9GV0Z28 (Durapatite)
SB  - IM
MH  - Biocompatible Materials/analysis/*chemistry
MH  - Cell Culture Techniques/*methods
MH  - Durapatite/analysis/*chemistry
MH  - Hot Temperature
MH  - Lasers
MH  - Manufactured Materials/analysis
MH  - Materials Testing
MH  - Particle Size
MH  - Polyethylenes/analysis/*chemistry
MH  - Porosity
MH  - *Prostheses and Implants
MH  - Surface Properties
MH  - Tissue Engineering/*methods
EDAT- 2006/07/01 09:00
MHDA- 2006/07/28 09:00
CRDT- 2006/07/01 09:00
PHST- 2006/07/01 09:00 [pubmed]
PHST- 2006/07/28 09:00 [medline]
PHST- 2006/07/01 09:00 [entrez]
AID - 10.1243/09544119JEIM67 [doi]
PST - ppublish
SO  - Proc Inst Mech Eng H. 2006 May;220(4):521-31. doi: 10.1243/09544119JEIM67.