PMID- 16816548
OWN - NLM
STAT- MEDLINE
DCOM- 20060929
LR  - 20180614
IS  - 1648-9144 (Electronic)
IS  - 1010-660X (Linking)
VI  - 42
IP  - 6
DP  - 2006
TI  - [Ecstasy toxicity].
PG  - 519-23
AB  - The substance, 3,4-methylenedioxymethamphetamine (MDMA) or ecstasy, is an 
      amphetamine derivate. A mistaken belief that it is a safe drug of low toxicity 
      and a long duration of action has led to its widespread popularity among 
      teenagers and young adults in recent years. Unfortunately, ecstasy use has 
      increased to epidemic proportions. In this review article pharmacokinetics and 
      pathophysiology of MDMA, general medical adverse effects, cardiovascular effects, 
      serotonin syndrome, hyponatremia, neurologic effects, hepatotoxicity, and 
      long-term neuropsychiatric effects, clinical features of toxicity, prehospital 
      and emergency department care problems, and mortality/morbidity, prophylactic 
      advices are discussed.
FAU - Reingardiene, Dagmara
AU  - Reingardiene D
AD  - Clinic of Intensive Care, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, 
      Lithuania.
LA  - lit
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Ekstazio toksiskumas.
PL  - Switzerland
TA  - Medicina (Kaunas)
JT  - Medicina (Kaunas, Lithuania)
JID - 9425208
RN  - 0 (Hallucinogens)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Cardiovascular Diseases/chemically induced
MH  - Emergencies
MH  - Hallucinogens/*adverse effects/pharmacokinetics
MH  - Hospitalization
MH  - Humans
MH  - Hyponatremia/chemically induced
MH  - Liver/drug effects
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*adverse effects/pharmacokinetics
MH  - Neurotoxicity Syndromes/etiology/physiopathology
MH  - Psychoses, Substance-Induced/etiology
MH  - Serotonin Syndrome/chemically induced
MH  - *Substance-Related Disorders/drug 
      therapy/epidemiology/mortality/physiopathology/prevention & control
MH  - Time Factors
RF  - 26
EDAT- 2006/07/04 09:00
MHDA- 2006/09/30 09:00
CRDT- 2006/07/04 09:00
PHST- 2006/07/04 09:00 [pubmed]
PHST- 2006/09/30 09:00 [medline]
PHST- 2006/07/04 09:00 [entrez]
AID - 0606-12l [pii]
PST - ppublish
SO  - Medicina (Kaunas). 2006;42(6):519-23.