PMID- 16820646
OWN - NLM
STAT- MEDLINE
DCOM- 20060818
LR  - 20220408
IS  - 1524-4539 (Electronic)
IS  - 0009-7322 (Linking)
VI  - 114
IP  - 1 Suppl
DP  - 2006 Jul 4
TI  - Repair of bicuspid aortic valves in patients with aortic regurgitation.
PG  - I610-6
AB  - BACKGROUND: Bicuspid aortic valve regurgitation can be caused by a defect in the 
      valve itself or by dysfunction of one or more components of the aortic root 
      complex. A successful repair thus requires correction of all aspects of the 
      problem simultaneously. We review our experience addressing both the valve and 
      the aortic root when correcting bicuspid valve regurgitation. METHODS AND 
      RESULTS: Between 1996 and 2004, we treated 68 patients for aortic regurgitation. 
      Thirty patients had isolated aortic regurgitation, and 38 had an associated 
      ascending aortic aneurysm. All patients were treated using a standardized and 
      integrated surgical technique, which included resection of the median raphe or 
      leaflet plication, subcommissural annuloplasty, reinforcement of the leaflet free 
      edge, and sinotubular junction plication. In the 38 patients with proximal aortic 
      dilatation, reimplantation or remodeling of the aortic root was performed. 
      Immediate postoperative echocardiography showed grade < or = 1 aortic 
      regurgitation in all patients. Three patients nonetheless needed an early 
      re-operation because of recurrent regurgitation. No hospital mortality was 
      observed. At a mean follow-up of 34 months after surgery, all patients were in 
      New York Heart Association (NYHA) class 1 or 2. Two patients needed a 
      re-operation (23 and 92 months, respectively). Echocardiographic follow-up showed 
      no progression of the regurgitation in 58 surviving patients. Four patients 
      progressed to grade 2 regurgitation. CONCLUSIONS: Our data indicate that 
      regurgitant bicuspid aortic valves, whether alone or in association with a 
      proximal aortic dilatation, can be repaired successfully provided that both the 
      valve and the aortic root problems are treated simultaneously.
FAU - El Khoury, Gebrine
AU  - El Khoury G
AD  - Department of Cardiovascular and Thoracic Surgery, Cliniques Universitaires 
      Saint-Luc, Brussels, Belgium. Elkhoury@chir.ucl.ac.be
FAU - Vanoverschelde, Jean-Louis
AU  - Vanoverschelde JL
FAU - Glineur, David
AU  - Glineur D
FAU - Pierard, Frederic
AU  - Pierard F
FAU - Verhelst, Robert R
AU  - Verhelst RR
FAU - Rubay, Jean
AU  - Rubay J
FAU - Funken, Jean-Christophe
AU  - Funken JC
FAU - Watremez, Christine
AU  - Watremez C
FAU - Astarci, Parla
AU  - Astarci P
FAU - Lacroix, Valerie
AU  - Lacroix V
FAU - Poncelet, Alain
AU  - Poncelet A
FAU - Noirhomme, Philippe
AU  - Noirhomme P
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aorta/surgery
MH  - Aortic Aneurysm/complications/surgery
MH  - Aortic Valve/pathology/surgery
MH  - Aortic Valve Insufficiency/complications/diagnostic imaging/*surgery
MH  - Cardiopulmonary Bypass
MH  - Disease Progression
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Recurrence
MH  - Reoperation
MH  - Retrospective Studies
MH  - *Suture Techniques
MH  - Treatment Outcome
MH  - Ultrasonography
EDAT- 2006/07/06 09:00
MHDA- 2006/08/19 09:00
CRDT- 2006/07/06 09:00
PHST- 2006/07/06 09:00 [pubmed]
PHST- 2006/08/19 09:00 [medline]
PHST- 2006/07/06 09:00 [entrez]
AID - 114/1_suppl/I-610 [pii]
AID - 10.1161/CIRCULATIONAHA.105.001594 [doi]
PST - ppublish
SO  - Circulation. 2006 Jul 4;114(1 Suppl):I610-6. doi: 
      10.1161/CIRCULATIONAHA.105.001594.