PMID- 16825768
OWN - NLM
STAT- MEDLINE
DCOM- 20060728
LR  - 20101118
IS  - 1424-859X (Electronic)
IS  - 1424-8581 (Linking)
VI  - 114
IP  - 2
DP  - 2006
TI  - Assignment of zebrafish genetic linkage groups to chromosomes.
PG  - 155-62
AB  - In this report the zebrafish genetic linkage groups are assigned to specific 
      chromosomes using fluorescence in situ hybridization (FISH) with BAC probes 
      containing genes mapped to each linkage group (LG). Chromosomes were identified 
      using a combination of relative size and arm ratios. The largest genetic maps 
      generally corresponded to the largest chromosomes, but genetic recombination 
      tended to be elevated in the smaller chromosomes and near telomeres. Large insert 
      clones containing genes near telomeres often hybridized to telomeres of multiple 
      chromosome pairs, suggesting the presence of shared subtelomeric repetitive DNAs 
      near telomeres. Evidence from comparative gene mapping in medaka, zebrafish, 
      pufferfish, and humans suggests that the linkage groups of these species have the 
      content of duplicate proto-chromosomes. However, these duplicate linkage groups 
      are not associated with chromosomes of similar size or morphology. This suggests 
      that considerable chromosome restructuring occurred subsequent to the genome 
      duplication in teleosts.
CI  - Copyright (c) 2006 S. Karger AG, Basel.
FAU - Phillips, R B
AU  - Phillips RB
AD  - Department of Biological Sciences, Washington State University, Vancouver 
      98686-9600, USA. phillipsr@vancouver.wsu.edu
FAU - Amores, A
AU  - Amores A
FAU - Morasch, M R
AU  - Morasch MR
FAU - Wilson, C
AU  - Wilson C
FAU - Postlethwait, J H
AU  - Postlethwait JH
LA  - eng
GR  - HD22486/HD/NICHD NIH HHS/United States
GR  - R01 GM62660/GM/NIGMS NIH HHS/United States
GR  - R01RR10715/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - Switzerland
TA  - Cytogenet Genome Res
JT  - Cytogenetic and genome research
JID - 101142708
SB  - IM
MH  - Animals
MH  - Cell Line
MH  - Chromosome Mapping
MH  - Chromosomes/*genetics
MH  - Genetic Linkage/*genetics
MH  - Humans
MH  - Karyotyping
MH  - Zebrafish/*genetics
EDAT- 2006/07/11 09:00
MHDA- 2006/07/29 09:00
CRDT- 2006/07/11 09:00
PHST- 2005/12/08 00:00 [received]
PHST- 2006/01/25 00:00 [accepted]
PHST- 2006/07/11 09:00 [pubmed]
PHST- 2006/07/29 09:00 [medline]
PHST- 2006/07/11 09:00 [entrez]
AID - 93332 [pii]
AID - 10.1159/000093332 [doi]
PST - ppublish
SO  - Cytogenet Genome Res. 2006;114(2):155-62. doi: 10.1159/000093332.