PMID- 16828180
OWN - NLM
STAT- MEDLINE
DCOM- 20070313
LR  - 20151119
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 116
IP  - 2
DP  - 2007 Mar 20
TI  - Late gadolinium-enhanced cardiovascular magnetic resonance identifies patients 
      with standardized definition of ischemic cardiomyopathy: a single centre 
      experience.
PG  - 167-73
AB  - BACKGROUND: Definition of ischemic cardiomyopathy (IC) is not always obvious, 
      which is why new criteria based on prognosis and the extent of the coronary 
      artery disease (CAD) have been proposed. In the present study, we assess the 
      capability of late gadolinium-enhanced cardiovascular magnetic resonance (CMR) 
      for predicting IC as determined by standardized criteria previously reported. 
      METHODS AND RESULTS: 123 patients with heart failure (HF) and left ventricular 
      (LV) systolic dysfunction, underwent both late gadolinium-enhanced CMR and 
      coronary angiography 37/123 (30%) of patients were assigned to the IC group and 
      86/123 (70%) to the non-IC group. Subendocardial late gadolinium enhancement 
      (LGE) was found in 35/37 (94%) of patients in the IC group, whereas only 12/86 
      (14%) had this distribution in the non-IC group (p<0.001). There was a 
      significant positive correlation between the extent of subendocardial LGE and 
      that of the CAD as determined by the CAD Prognostic Index (r=0.78, p<0.01), the 
      number of coronary stenoses > or = 50% (r=0.76, p<0.01) and the number of 
      coronary stenoses of any percentage (r=0.70, p<0.01). CONCLUSION: In patients 
      with HF and LV systolic dysfunction presence of subendocardial LGE makes an 
      excellent indicator of underlying significant CAD, and the extent of the LGE 
      correlates with the severity of the disease. It is therefore appealing as a 
      method for diagnosing IC.
FAU - Soriano, Carlos J
AU  - Soriano CJ
AD  - Servicio de Cardiologia, Consorcio Hospital General Universitario de Valencia, 
      Spain.
FAU - Ridocci, Francisco
AU  - Ridocci F
FAU - Estornell, Jordi
AU  - Estornell J
FAU - Perez-Bosca, Jose L
AU  - Perez-Bosca JL
FAU - Pomar, Francisco
AU  - Pomar F
FAU - Trigo, Alberto
AU  - Trigo A
FAU - Planas, Ana
AU  - Planas A
FAU - Nadal, Mercedes
AU  - Nadal M
FAU - Jacas, Victoria
AU  - Jacas V
FAU - Martinez, Vicente
AU  - Martinez V
FAU - Paya, Rafael
AU  - Paya R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20060707
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Aged
MH  - Cardiac Output, Low/complications/diagnosis
MH  - Cardiovascular System/*pathology
MH  - Coronary Angiography
MH  - Coronary Artery Disease/diagnosis
MH  - Endocardium/pathology
MH  - Female
MH  - *Gadolinium
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Myocardial Ischemia/*diagnosis
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Severity of Illness Index
MH  - Systole
MH  - Ventricular Dysfunction, Left/complications/diagnosis/physiopathology
EDAT- 2006/07/11 09:00
MHDA- 2007/03/14 09:00
CRDT- 2006/07/11 09:00
PHST- 2005/11/23 00:00 [received]
PHST- 2006/03/07 00:00 [revised]
PHST- 2006/03/11 00:00 [accepted]
PHST- 2006/07/11 09:00 [pubmed]
PHST- 2007/03/14 09:00 [medline]
PHST- 2006/07/11 09:00 [entrez]
AID - S0167-5273(06)00440-2 [pii]
AID - 10.1016/j.ijcard.2006.03.040 [doi]
PST - ppublish
SO  - Int J Cardiol. 2007 Mar 20;116(2):167-73. doi: 10.1016/j.ijcard.2006.03.040. Epub 
      2006 Jul 7.