PMID- 16835984 OWN - NLM STAT- MEDLINE DCOM- 20060726 LR - 20190117 IS - 1726-4901 (Print) IS - 1726-4901 (Linking) VI - 69 IP - 5 DP - 2006 May TI - Coronary artery bypass grafting in patients with left ventricular dysfunction. PG - 218-23 AB - BACKGROUND: Coronary artery bypass grafting surgery (CABG) remains a challenge for patients with coronary artery disease and left ventricular (LV) dysfunction. The aim of this study was to evaluate the result of CABG in patients with LV dysfunction. METHODS: Medical records of 1,847 patients who underwent primary, isolated CABG at Taipei Veterans General Hospital from January 1, 1991 to December 31, 2002, were reviewed. The mortality rate associated with clinical and operative variables was compared between patients with LV ejection fraction (LVEF) > or = 35% and patients with LVEF < 35%. RESULTS: Patients with LVEF < 35% had more episodes of myocardial infarction (57.5% vs 28.9%, p < 0.001) and history of congestive heart failure (18.1% vs 3.2%, p < 0.001), higher New York Heart Association (NYHA) class, and higher angina class. Longer cardiopulmonary bypass time (147 +/- 44 minutes vs 137 +/- 40 minutes, p < 0.001) but fewer left internal mammary artery (LIMA) grafts (46.8% vs 65.7%, p < 0.001) were used in patients with LVEF < 35%. Patients with LVEF < 35% had significantly higher hospital mortality (6.6% vs 2.2%, p < 0.001), higher major morbidity (23.3% vs 16.1%, p < 0.01), and longer hospital stay (25 +/- 23 days vs 21 +/- 16 days, p < 0.01). CONCLUSION: Although patients with LV dysfunction had higher mortality and morbidity, CABG could be done in these high-risk patients with acceptable results. FAU - Wu, Fei-Yi AU - Wu FY AD - Division of Cardiovascular Surgery, Department of Surgery, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital, Taiwan, ROC. FAU - Lu, Yen-Chou AU - Lu YC FAU - Lai, Shiau-Ting AU - Lai ST FAU - Weng, Zen-Chung AU - Weng ZC FAU - Huang, Cheng-Hsiung AU - Huang CH LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Netherlands TA - J Chin Med Assoc JT - Journal of the Chinese Medical Association : JCMA JID - 101174817 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - *Coronary Artery Bypass MH - Female MH - Humans MH - Male MH - Middle Aged MH - Stroke Volume MH - Ventricular Dysfunction, Left/mortality/physiopathology/*surgery MH - Ventricular Function, Left EDAT- 2006/07/14 09:00 MHDA- 2006/07/27 09:00 CRDT- 2006/07/14 09:00 PHST- 2006/07/14 09:00 [pubmed] PHST- 2006/07/27 09:00 [medline] PHST- 2006/07/14 09:00 [entrez] AID - S1726-4901(09)70222-9 [pii] AID - 10.1016/S1726-4901(09)70222-9 [doi] PST - ppublish SO - J Chin Med Assoc. 2006 May;69(5):218-23. doi: 10.1016/S1726-4901(09)70222-9.