PMID- 16839469
OWN - NLM
STAT- MEDLINE
DCOM- 20061127
LR  - 20191210
IS  - 0146-4760 (Print)
IS  - 0146-4760 (Linking)
VI  - 30
IP  - 5
DP  - 2006 Jun
TI  - Prevalence of use study for amphetamine (AMP), methamphetamine (MAMP), 
      3,4-methylenedioxy-amphetamine (MDA), 3,4-methylenedioxy-methamphetamine (MDMA), 
      and 3,4-methylenedioxy-ethylamphetamine (MDEA) in military entrance processing 
      stations (MEPS) specimens.
PG  - 319-22
AB  - The Roche Abuscreen Onlinetrade mark Amphetamine immunoassay (IA), modified to 
      include sodium periodate, and the Microgenics DRI Ecstasy IA were used to 
      determine the prevalence of amphetamine (AMP), methamphetamine (MAMP), 
      3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA), 
      and 3,4-methylenedioxyethylamphetamine (MDEA) in urine specimens from applicants 
      seeking to join the United States Armed Forces. Over a 4-month period, a total of 
      85,658 specimens were IA screened using the Department of Defense 500 ng/mL 
      administrative cutoff level for AMP and MDMA. All presumptively positive 
      specimens were confirmed using a solid-phase extraction procedure coupled with 
      simultaneous analysis of AMP, MAMP, MDA, MDMA, and MDEA by fast gas 
      chromatography-mass spectrometry using the same cutoff levels as the IA. The 
      Roche Online Amphetamine IA identified 216 specimens as presumptively positive; 
      of these, 70 specimens confirmed positive for AMP and 87 specimens confirmed 
      positive for AMP and/or MAMP, resulting in a confirmation rate of 73%. The 
      Microgenics DRI Ecstasy IA identified eight specimens as presumptively positive; 
      of these, five specimens confirmed positive for MDMA and/or MDA, resulting in a 
      confirmation rate of 63%. The total use prevalence for AMP, MAMP, MDA, MDMA, 
      and/or MDEA in military entrance processing stations specimens over the testing 
      period was determined to be 0.19%.
FAU - Klette, Kevin L
AU  - Klette KL
AD  - Navy Drug Screening Laboratory, 320B B Street, Great Lakes, Illinois 60088-2815, 
      USA. klklette@nhgl.med.navy.mil
FAU - Kettle, Aaron R
AU  - Kettle AR
FAU - Jamerson, Matthew H
AU  - Jamerson MH
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Anal Toxicol
JT  - Journal of analytical toxicology
JID - 7705085
RN  - 0 (Amphetamines)
RN  - 0 (Illicit Drugs)
SB  - IM
MH  - Amphetamines/*urine
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Illicit Drugs/urine
MH  - *Military Personnel
MH  - Substance Abuse Detection
MH  - United States
EDAT- 2006/07/15 09:00
MHDA- 2006/12/09 09:00
CRDT- 2006/07/15 09:00
PHST- 2006/07/15 09:00 [pubmed]
PHST- 2006/12/09 09:00 [medline]
PHST- 2006/07/15 09:00 [entrez]
AID - 10.1093/jat/30.5.319 [doi]
PST - ppublish
SO  - J Anal Toxicol. 2006 Jun;30(5):319-22. doi: 10.1093/jat/30.5.319.