PMID- 16850142
OWN - NLM
STAT- MEDLINE
DCOM- 20061221
LR  - 20181113
IS  - 0364-2313 (Print)
IS  - 0364-2313 (Linking)
VI  - 30
IP  - 10
DP  - 2006 Oct
TI  - Outcomes of surgery for intraductal papillary mucinous neoplasms of the pancreas.
PG  - 1909-14; discussion 1915
AB  - BACKGROUND: Our objective was to evaluate outcomes of surgery for intraductal 
      papillary mucinous neoplasms of the pancreas (IPMN) in terms of the 
      clinicopathological features. METHODS: Fifty-seven patients with IPMN were 
      examined using clinicopathological analyses to evaluate appropriate surgical 
      treatment, including total pancreatectomy (TP). IPMN was classified into two 
      types: main-duct type (MD, n = 33) and branch-duct type (BD, n = 24). RESULTS: 
      Ultrasound (US) and computed tomography (CT) examinations easily revealed the 
      main site of the lesions. Intraoperative US was the most useful device for 
      diagnosis of lateral spreading, and accuracy rates were 74% for MD and 96% for 
      BD. TP was performed on 16 patients and was appropriate for removing neoplastic 
      lesions with malignancy or malignant potential in 12. Three patients who 
      underwent partial pancreatectomy with involved cancer died of progressive 
      disease. MD is a strong predictive factor in malignancy and indicative of TP. 
      Concerning long-term outcomes, 5 of 16 patients suffered from severe 
      hypoglycemia, and 2 of 16 died from this condition. CONCLUSION: Partial resection 
      with cancer clearance was applied for BD-type IPMN. TP should be performed on 
      selected patients with MD-type IPMN.
FAU - Fujino, Yasuhiro
AU  - Fujino Y
AD  - Division of Gastroenterological Surgery, Department of Clinical Molecular 
      Medicine, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, 
      Chuo-ku, Kobe, 650-0017, Japan. yasu120@med.kobe-u.ac.jp
FAU - Suzuki, Yasuyuki
AU  - Suzuki Y
FAU - Yoshikawa, Takuro
AU  - Yoshikawa T
FAU - Ajiki, Tetsuo
AU  - Ajiki T
FAU - Ueda, Takashi
AU  - Ueda T
FAU - Matsumoto, Ippei
AU  - Matsumoto I
FAU - Kuroda, Yoshikazu
AU  - Kuroda Y
LA  - eng
PT  - Journal Article
PL  - United States
TA  - World J Surg
JT  - World journal of surgery
JID - 7704052
SB  - IM
MH  - Adult
MH  - Aged
MH  - Carcinoma, Pancreatic Ductal/diagnosis/mortality/*surgery
MH  - Cholangiopancreatography, Endoscopic Retrograde
MH  - Cholangiopancreatography, Magnetic Resonance
MH  - Diagnosis, Differential
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pancreatectomy/*methods
MH  - Pancreatic Neoplasms/diagnosis/mortality/*surgery
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Time Factors
MH  - Tomography, X-Ray Computed
MH  - Treatment Outcome
EDAT- 2006/07/20 09:00
MHDA- 2006/12/22 09:00
CRDT- 2006/07/20 09:00
PHST- 2006/07/20 09:00 [pubmed]
PHST- 2006/12/22 09:00 [medline]
PHST- 2006/07/20 09:00 [entrez]
AID - 10.1007/s00268-006-0051-3 [doi]
PST - ppublish
SO  - World J Surg. 2006 Oct;30(10):1909-14; discussion 1915. doi: 
      10.1007/s00268-006-0051-3.