PMID- 16850170
OWN - NLM
STAT- MEDLINE
DCOM- 20061027
LR  - 20161124
IS  - 0723-5003 (Print)
IS  - 0723-5003 (Linking)
VI  - 101
IP  - 7
DP  - 2006 Jul 15
TI  - [Endoscopic ultrasound imaging in neuroendocrine pancreatic tumors. A critical 
      analysis].
PG  - 546-51
AB  - Endoscopic ultrasound enables imaging of the pancreas with high resolution. 
      Today, it is considered to be the best preoperative imaging procedure in 
      insulinomas. Since the result of endoscopic ultrasound may influence surgical 
      strategy (minimally invasive approach), it needs to be performed in all patients. 
      Furthermore, positive endoscopic ultrasound is able to confirm the diagnosis of 
      insulinoma, since fasting test also may have been positive due to the intake of 
      sulfonylureas or glinides which may have been missed Patiin toxicological 
      analysis. However, false-positive and false-negative results always have to be 
      taken into account. Gastrinomas which are located in the pancreas are usually 
      detected by endoscopic ultrasound, yet often missed when localized in the 
      duodenal wall. Thus, endoscopic ultrasound is not very helpful in treatment 
      planning here. In multiple endocrine neoplasia type 1 (MEN1), endoscopic 
      ultrasound is by far the best method to analyze the morphology of the pancreas. 
      Clinical consequences are difficult, since the unclear prognosis of very small 
      neuroendocrine pancreatic tumors in MEN1 on the one hand and possible side 
      effects of surgical treatment (perioperative complications, diabetes mellitus 
      following pancreatic surgery) on the other hand need to be discussed.
FAU - Kann, Peter Herbert
AU  - Kann PH
AD  - Bereich Endokrinologie and Diabetologie, Zentrum fur Innere Medizin, 
      Universitatsklinikum Giessen und Marburg, Standort Marburg, Fachbereich Medizin 
      der Philipps-Universitat Marburg, Marburg. kannp@med.uni-marburg.de
LA  - ger
PT  - Journal Article
PT  - Review
TT  - Endosonographische Bildgebung bei neuroendokrinen Pankreastumoren: Eine kritische 
      Bestandsaufnahme.
PL  - Germany
TA  - Med Klin (Munich)
JT  - Medizinische Klinik (Munich, Germany : 1983)
JID - 8303501
SB  - IM
MH  - Carcinoma, Neuroendocrine/*diagnostic imaging/surgery
MH  - Diagnosis, Differential
MH  - Duodenal Neoplasms/diagnostic imaging/surgery
MH  - *Endosonography
MH  - Gastrinoma/diagnostic imaging/surgery
MH  - Humans
MH  - Insulinoma/diagnostic imaging/surgery
MH  - Multiple Endocrine Neoplasia Type 1/diagnostic imaging/surgery
MH  - Pancreas/diagnostic imaging/surgery
MH  - Pancreatic Neoplasms/*diagnostic imaging/surgery
MH  - Preoperative Care
MH  - Sensitivity and Specificity
RF  - 27
EDAT- 2006/07/20 09:00
MHDA- 2006/10/28 09:00
CRDT- 2006/07/20 09:00
PHST- 2006/01/10 00:00 [received]
PHST- 2006/03/22 00:00 [revised]
PHST- 2006/07/20 09:00 [pubmed]
PHST- 2006/10/28 09:00 [medline]
PHST- 2006/07/20 09:00 [entrez]
AID - 10.1007/s00063-006-1064-2 [doi]
PST - ppublish
SO  - Med Klin (Munich). 2006 Jul 15;101(7):546-51. doi: 10.1007/s00063-006-1064-2.