PMID- 1685128
OWN - NLM
STAT- MEDLINE
DCOM- 19920221
LR  - 20190721
IS  - 0014-4819 (Print)
IS  - 0014-4819 (Linking)
VI  - 87
IP  - 2
DP  - 1991
TI  - Tyrosine hydroxylase-like immunoreactive neurons in the olfactory bulb of the 
      snake, Elaphe quadrivirgata, with special reference to the colocalization of 
      tyrosine hydroxylase- and GABA-like immunoreactivities.
PG  - 353-62
AB  - The distribution and structural features of tyrosine hydroxylase-like 
      immunoreactive (TH-LI) neurons were studied in the olfactory bulb of a snake, 
      Elaphe quadrivirgata, by using pre- and post-embedding immunocytochemistry at the 
      light microscopic level. In contrast to rodent olfactory bulbs previously 
      reported, many TH-LI neurons were seen not only in the main olfactory bulb (MOB) 
      but also in the accessory olfactory bulb (AOB). With regard to the TH-like 
      immunoreactivity, there appeared no appreciable differences between MOB and AOB. 
      As in mammalian MOB, the majority of TH-LI neurons were clustered in the 
      periglomerular region and appeared to send their dendritic branches into 
      glomeruli, which as a whole make an intense TH-LI band in the glomerular layer 
      (GML). In the external plexiform/mitral cell layer (EPL/ML) of MOB and AOB as 
      well as in the outer sublamina of the internal plexiform layer (OSL) of AOB, an 
      appreciable number of TH-LI neurons were scattered, extending dendritic processes 
      which appeared to make a loose meshwork. TH-LI neurons in EPL/ML (including OSL) 
      appeared to consist of at least two morphologically different types. The first 
      had a small perikaryon and one or two smooth dendrites which usually extended to 
      GML and were frequently confirmed to enter into glomeruli. The second had a 
      larger perikaryon and 2-3 dendrites which branched into several varicose 
      processes extending in EPL/ML/OSL but appeared not to enter into glomeruli. The 
      TH-like immunoreactivity was rarely seen in the internal plexiform layer and 
      internal granule cell layer. The colocalization of GABA-like and TH-like 
      immunoreactivities was further studied. Almost all TH-LI neurons in both 
      EPL/ML/OSL and GML contained GABA-like immunoreactivity irrespectively of the 
      type of TH-LI cells.
FAU - Kosaka, T
AU  - Kosaka T
AD  - Department of Anatomy, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
FAU - Kosaka, K
AU  - Kosaka K
FAU - Nagatsu, I
AU  - Nagatsu I
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Exp Brain Res
JT  - Experimental brain research
JID - 0043312
RN  - 0 (Antibodies, Monoclonal)
RN  - 56-12-2 (gamma-Aminobutyric Acid)
RN  - EC 1.14.16.2 (Tyrosine 3-Monooxygenase)
SB  - IM
MH  - Animals
MH  - Antibodies, Monoclonal
MH  - Immunoenzyme Techniques
MH  - Immunohistochemistry
MH  - Neurons/*cytology
MH  - Olfactory Bulb/*cytology/enzymology
MH  - Snakes
MH  - Telencephalon/cytology/enzymology
MH  - Tyrosine 3-Monooxygenase/*analysis
MH  - gamma-Aminobutyric Acid/*analysis
EDAT- 1991/01/01 00:00
MHDA- 1991/01/01 00:01
CRDT- 1991/01/01 00:00
PHST- 1991/01/01 00:00 [pubmed]
PHST- 1991/01/01 00:01 [medline]
PHST- 1991/01/01 00:00 [entrez]
AID - 10.1007/BF00231852 [doi]
PST - ppublish
SO  - Exp Brain Res. 1991;87(2):353-62. doi: 10.1007/BF00231852.