PMID- 16866203
OWN - NLM
STAT- MEDLINE
DCOM- 20060828
LR  - 20190902
IS  - 0425-1644 (Print)
IS  - 0425-1644 (Linking)
VI  - 38
IP  - 4
DP  - 2006 Jul
TI  - Prevalence of gastric squamous ulceration in horses with abdominal pain.
PG  - 347-9
AB  - REASONS FOR PERFORMING STUDY: Prevalence of gastric ulcerations differs widely 
      according to breed and circumstances of management. Further study of the 
      biological variables involved is required in order to identify more exactly the 
      reasons for the reported range. OBJECTIVES: The objectives of this present study, 
      which do not appear to have been addressed previously in the literature, were 1) 
      the prevalence of gastric ulceration in horses with abdominal pain. 2) difference 
      in prevalence in horses responding to medical therapy and those requiring 
      surgical intervention. 3) whether gastric ulceration is associated with any 
      particular gastrointestinal tract lesion. METHODS: Horses were included in the 
      study if gastroscopy was performed within 24 h of presentation. The presence and 
      grade of gastric ulceration was recorded together with the medical records. Data 
      were analysed categorically using a Fisher's exact test or Chi-squared test. 
      RESULTS: One hundred horses met the selection criteria. Forty-nine percent 
      (49/100) of horses had gastric ulceration, 63% (63/100) responded to medical 
      therapy and 37% (37/100) to surgical intervention, and prevalence was higher in 
      the former (59%) than the latter (32%). Horses with duodenitis-proximal jejunitis 
      (DPJ) had a trend towards higher prevalence of gastric ulceration compared to 
      those with other GI lesions. Sixty-eight percent (13/19) of horses diagnosed with 
      DPJ, 32% (8/25) with a large colon impaction and 14% (1/7) with large colon 
      volvulus had gastric ulceration. CONCLUSIONS: The presence of gastric ulceration 
      in all horses with abdominal pain was moderate. Horses responding to medical 
      therapy had a higher prevalence of gastric ulceration compared to horses 
      requiring surgery and there was a trend towards higher prevalence in cases of DPJ 
      compared to other GI lesions. There was not a statistically significant 
      difference in gastric ulceration detected between specific lesions, including 
      large colon impactions and large colon volvulus. POTENTIAL RELEVANCE: The 
      clinical relevance of ulceration is still unclear and further studies are 
      required to differentiate between incidental and clinically important gastric 
      ulceration.
FAU - Dukti, S A
AU  - Dukti SA
AD  - Rood and Riddle Equine Hospital, Lexington, Kentucky 40580, USA.
FAU - Perkins, S
AU  - Perkins S
FAU - Murphy, J
AU  - Murphy J
FAU - Barr, B
AU  - Barr B
FAU - Boston, R
AU  - Boston R
FAU - Southwood, L L
AU  - Southwood LL
FAU - Bernard, W
AU  - Bernard W
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Equine Vet J
JT  - Equine veterinary journal
JID - 0173320
RN  - 0 (Anti-Inflammatory Agents)
RN  - 0 (Anti-Inflammatory Agents, Non-Steroidal)
SB  - IM
MH  - Abdominal Pain/epidemiology/etiology/pathology/veterinary
MH  - Animals
MH  - Anti-Inflammatory Agents/therapeutic use
MH  - Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
MH  - Chi-Square Distribution
MH  - Female
MH  - Gastrointestinal Diseases/epidemiology/pathology/therapy/*veterinary
MH  - Gastroscopy/methods/veterinary
MH  - Horse Diseases/drug therapy/*epidemiology/pathology/surgery
MH  - Horses
MH  - Male
MH  - Prevalence
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Stomach Ulcer/epidemiology/pathology/therapy/*veterinary
MH  - Surgery, Veterinary/methods
MH  - Treatment Outcome
EDAT- 2006/07/27 09:00
MHDA- 2006/08/29 09:00
CRDT- 2006/07/27 09:00
PHST- 2006/07/27 09:00 [pubmed]
PHST- 2006/08/29 09:00 [medline]
PHST- 2006/07/27 09:00 [entrez]
AID - 10.2746/042516406777749164 [doi]
PST - ppublish
SO  - Equine Vet J. 2006 Jul;38(4):347-9. doi: 10.2746/042516406777749164.