PMID- 16866887
OWN - NLM
STAT- MEDLINE
DCOM- 20060818
LR  - 20221207
IS  - 0001-2815 (Print)
IS  - 0001-2815 (Linking)
VI  - 68
IP  - 2
DP  - 2006 Aug
TI  - Four novel human leukocyte antigen-DQA1 alleles identified in the Korean 
      population.
PG  - 167-72
AB  - Four novel human leukocyte antigen (HLA)-DQA1 alleles have been characterized by 
      direct DNA sequencing of coding exons 1-4. All the novel alleles exhibited a 
      single nucleotide substitution either in exon 3 or in exon 4 when compared with 
      previously defined alleles. Thus, it is likely that alleles were generated by 
      point mutation from pre-existing alleles in the population. Substitutions 
      resulted in either a silent (DQA1*010203) or an amino acid change (DQA1*0506, 
      DQA1*0507, and DQA1*0508). The substituted sites were both previously known 
      polymorphic and conserved positions. Putative haplotypes associated with the 
      novel alleles were deduced based on the HLA types shared by the individuals 
      carrying a novel allele or from previously reported population data.
FAU - Lee, K W
AU  - Lee KW
AD  - Hallym Institution for Genome Application, Hallym University Sacred Heart 
      Hospital, Anyang, Kyungki-Do, Korea. leekw@hallym.or.kr
FAU - Jung, Y-A
AU  - Jung YA
FAU - Oh, D H
AU  - Oh DH
LA  - eng
SI  - GENBANK/DQ178400
SI  - GENBANK/DQ178401
SI  - GENBANK/DQ178402
SI  - GENBANK/DQ178403
SI  - GENBANK/DQ178404
SI  - GENBANK/DQ178405
SI  - GENBANK/DQ178406
SI  - GENBANK/DQ178407
SI  - GENBANK/DQ178408
SI  - GENBANK/DQ178409
SI  - GENBANK/DQ178410
SI  - GENBANK/DQ178411
SI  - GENBANK/DQ178412
SI  - GENBANK/DQ178413
SI  - GENBANK/DQ178414
SI  - GENBANK/DQ178415
PT  - Journal Article
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-DQ Antigens)
RN  - 0 (HLA-DQ alpha-Chains)
RN  - 0 (HLA-DQA1 antigen)
SB  - IM
MH  - Alleles
MH  - Asian People/*genetics
MH  - Base Sequence
MH  - Exons/genetics
MH  - HLA-DQ Antigens/*genetics
MH  - HLA-DQ alpha-Chains
MH  - Humans
MH  - Korea
MH  - Molecular Sequence Data
MH  - Point Mutation
MH  - Polymerase Chain Reaction
MH  - *Polymorphism, Single Nucleotide
MH  - Sequence Analysis, DNA
EDAT- 2006/07/27 09:00
MHDA- 2006/08/19 09:00
CRDT- 2006/07/27 09:00
PHST- 2006/07/27 09:00 [pubmed]
PHST- 2006/08/19 09:00 [medline]
PHST- 2006/07/27 09:00 [entrez]
AID - TAN645 [pii]
AID - 10.1111/j.1399-0039.2006.00645.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2006 Aug;68(2):167-72. doi: 10.1111/j.1399-0039.2006.00645.x.