PMID- 16868348 OWN - NLM STAT- MEDLINE DCOM- 20061120 LR - 20191210 IS - 0967-3334 (Print) IS - 0967-3334 (Linking) VI - 27 IP - 9 DP - 2006 Sep TI - Impedance cardiography revisited. PG - 817-27 AB - Previously reported comparisons between cardiac output (CO) results in patients with cardiac conditions measured by thoracic impedance cardiography (TIC) versus thermodilution (TD) reveal upper and lower limits of agreement with two standard deviations (2SD) of approximately +/-2.2 l min(-1), a 44% disparity between the two technologies. We show here that if the electrodes are placed on one wrist and on a contralateral ankle instead of on the chest, a configuration designated as regional impedance cardiography (RIC), the 2SD limit of agreement between RIC and TD is +/-1.0 l min(-1), approximately 20% disparity between the two methods. To compare the performances of the TIC and RIC algorithms, the raw data of peripheral impedance changes yielded by RIC in 43 cardiac patients were used here for software processing and calculating the CO with the TIC algorithm. The 2SD between the TIC and TD was +/-1.7 l min(-1), and after annexing the correcting factors of the RIC formula to the TIC formula, the disparity between TIC and TD further declined to +/-1.25 l min(-1). CONCLUSIONS: (1) in cardiac conditions, the RIC technology is twice as accurate as TIC; (2) the advantage of RIC is the use of peripheral rather than thoracic impedance signals, supported by correcting factors. FAU - Cotter, G AU - Cotter G AD - Division of Clinical Pharmacology, Duke University Medical Center, Durham, NC, USA. gad.cotter@duke.edu FAU - Schachner, A AU - Schachner A FAU - Sasson, L AU - Sasson L FAU - Dekel, H AU - Dekel H FAU - Moshkovitz, Y AU - Moshkovitz Y LA - eng PT - Comparative Study PT - Evaluation Study PT - Journal Article PT - Validation Study DEP - 20060705 PL - England TA - Physiol Meas JT - Physiological measurement JID - 9306921 SB - IM MH - *Algorithms MH - *Cardiac Output MH - Cardiography, Impedance/*methods MH - Diagnosis, Computer-Assisted/*methods MH - Humans MH - Reproducibility of Results MH - Retrospective Studies MH - Sensitivity and Specificity MH - *Software EDAT- 2006/07/27 09:00 MHDA- 2006/12/09 09:00 CRDT- 2006/07/27 09:00 PHST- 2006/07/27 09:00 [pubmed] PHST- 2006/12/09 09:00 [medline] PHST- 2006/07/27 09:00 [entrez] AID - S0967-3334(06)18563-9 [pii] AID - 10.1088/0967-3334/27/9/005 [doi] PST - ppublish SO - Physiol Meas. 2006 Sep;27(9):817-27. doi: 10.1088/0967-3334/27/9/005. Epub 2006 Jul 5.