PMID- 16887436 OWN - NLM STAT- MEDLINE DCOM- 20060907 LR - 20071115 IS - 0022-3476 (Print) IS - 0022-3476 (Linking) VI - 149 IP - 2 DP - 2006 Aug TI - Comparison of classifications for heart failure in children undergoing valvular surgery. PG - 210-5 AB - OBJECTIVES: To characterize correlations between clinical classifications of heart failure and diagnostic workup. STUDY DESIGN: Pre- and postoperative characteristics of 20 children with heart failure secondary to valvular rheumatic disease were studied. RESULTS: Both scoring systems correlated with N-terminal pro-brain natriuretic peptide (N-proBNP) but not with troponin I (TnI). The PHFI correlated with N-proBNP, end-systolic wall stress, left ventricular mass index and left atrium to aorta diameter ratio. No correlation could be established between modified Ross score, or the New York Heart Association (NYHA) grade and echocardiographic measurements. Cardiothoracic and Sokolow indexes were correlated with the PHFI as well as to the NYHA classification. CONCLUSION: In this study, PHFI seems better correlated with radiologic, electrocardiographic, echocardiographic, and biologic assessment of heart failure in children. Clinical severity was correlated with N-proBNP but not with TnI. FAU - Tissieres, Pierre AU - Tissieres P AD - Cardiology Unit, Children's Hospital of Geneva, Geneva, Switzerland. FAU - Aggoun, Yacine AU - Aggoun Y FAU - Da Cruz, Eduardo AU - Da Cruz E FAU - Sierra, Jorge AU - Sierra J FAU - Mensi, Noury AU - Mensi N FAU - Kalangos, Afksendyios AU - Kalangos A FAU - Beghetti, Maurice AU - Beghetti M LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Pediatr JT - The Journal of pediatrics JID - 0375410 RN - 0 (Peptide Fragments) RN - 0 (Troponin) RN - 0 (pro-brain natriuretic peptide (1-76)) RN - 114471-18-0 (Natriuretic Peptide, Brain) SB - IM MH - Brain/metabolism MH - Cardiac Surgical Procedures/methods MH - Child MH - Echocardiography MH - Electrocardiography MH - Female MH - Heart Atria/pathology MH - Heart Failure/complications/*diagnosis/*surgery MH - Heart Valves/*pathology/*surgery MH - Heart Ventricles/pathology MH - Hepatomegaly/complications MH - Humans MH - Male MH - Natriuretic Peptide, Brain/metabolism MH - Peptide Fragments/metabolism MH - Rheumatic Heart Disease/complications/pathology MH - Severity of Illness Index MH - Troponin/metabolism EDAT- 2006/08/05 09:00 MHDA- 2006/09/08 09:00 CRDT- 2006/08/05 09:00 PHST- 2005/08/04 00:00 [received] PHST- 2006/01/25 00:00 [revised] PHST- 2006/04/03 00:00 [accepted] PHST- 2006/08/05 09:00 [pubmed] PHST- 2006/09/08 09:00 [medline] PHST- 2006/08/05 09:00 [entrez] AID - S0022-3476(06)00273-3 [pii] AID - 10.1016/j.jpeds.2006.04.006 [doi] PST - ppublish SO - J Pediatr. 2006 Aug;149(2):210-5. doi: 10.1016/j.jpeds.2006.04.006.