PMID- 16887729
OWN - NLM
STAT- MEDLINE
DCOM- 20060928
LR  - 20151119
IS  - 1477-8939 (Print)
IS  - 1477-8939 (Linking)
VI  - 4
IP  - 2
DP  - 2006 Mar
TI  - Malaria prevention and stand-by emergency treatment among Japanese travelers.
PG  - 81-5
AB  - BACKGROUND: While chemoprophylaxis remains the safest option for most travelers 
      to malaria high-risk areas, stand-by emergency treatment (SBET) may also be a 
      sensible option especially for travelers to low-risk areas, due to the possible 
      adverse effects (AEs) of prophylactic antimalarials. However, studies on the 
      suitability of SBET actually implemented by travelers are scarce, especially 
      those targeting Japanese travelers. We investigated to what extent malaria 
      prevention measures are taken and how effectively SBET is used by Japanese 
      travelers to malaria-endemic areas. MATERIALS AND METHODS: A questionnaire study 
      was conducted targeting Japanese travelers who visited quarantine stations for 
      pre-travel health advice and who had previously visited malaria-endemic areas as 
      defined by the World Health Organization (N = 160). RESULTS: The results showed 
      that only a minority (13%) of travelers to malaria-endemic areas took 
      chemoprophylaxis. Although most (89%) of the SBET users (N = 9) took antimalarial 
      drugs when they experienced both fever and chills, characteristic of clinical 
      malaria, there were several problems related to SBET. Some (22%) of the subjects 
      conducted SBET less than 7 days after entering the area, most (89%) of them did 
      so when a medical facility was readily accessible, and many (56%) failed to seek 
      medical attention soon after SBET or did not at all. CONCLUSIONS: Japanese 
      travelers to malaria-endemic areas seemed less protected with the use of 
      chemoprophylaxis. Furthermore, problems related to SBET among Japanese travelers 
      were identified. These should be taken into full consideration when educating 
      both travelers and travel health professionals to avoid risks of malaria and 
      possible AEs of antimalarial drugs.
FAU - Kimura, Mikio
AU  - Kimura M
AD  - Infectious Disease Surveillance Center, National Institute of Infectious 
      Diseases, Shinjuku-ku, Tokyo, Japan. kimumiki@nih.go.jp
FAU - Kawakami, Keiko
AU  - Kawakami K
FAU - Hashimoto, Michiko
AU  - Hashimoto M
FAU - Hamada, Masaru
AU  - Hamada M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Travel Med Infect Dis
JT  - Travel medicine and infectious disease
JID - 101230758
RN  - 0 (Antimalarials)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antimalarials/*administration & dosage
MH  - Chemoprevention/statistics & numerical data
MH  - Cross-Sectional Studies
MH  - Developing Countries
MH  - Female
MH  - Humans
MH  - Japan
MH  - Malaria/*drug therapy/*prevention & control
MH  - Male
MH  - Middle Aged
MH  - Patient Compliance/statistics & numerical data
MH  - Surveys and Questionnaires
MH  - Time Factors
MH  - *Travel
EDAT- 2006/08/05 09:00
MHDA- 2006/09/29 09:00
CRDT- 2006/08/05 09:00
PHST- 2004/12/16 00:00 [received]
PHST- 2005/03/22 00:00 [revised]
PHST- 2005/03/23 00:00 [accepted]
PHST- 2006/08/05 09:00 [pubmed]
PHST- 2006/09/29 09:00 [medline]
PHST- 2006/08/05 09:00 [entrez]
AID - S1477-8939(05)00033-5 [pii]
AID - 10.1016/j.tmaid.2005.03.001 [doi]
PST - ppublish
SO  - Travel Med Infect Dis. 2006 Mar;4(2):81-5. doi: 10.1016/j.tmaid.2005.03.001.