PMID- 16896493
OWN - NLM
STAT- MEDLINE
DCOM- 20070503
LR  - 20191110
IS  - 0716-1018 (Print)
IS  - 0716-1018 (Linking)
VI  - 23
IP  - 3
DP  - 2006 Sep
TI  - [Pneumocystis jiroveci pneumonia characteristics in adults with AIDS with or 
      without antiretroviral therapy].
PG  - 215-9
AB  - Highly active antiretroviral therapy (HAART) has changed the epidemiology of 
      Pneumocystis jiroveci pneumonia (PCP) in AIDS patients. Global incidence of PCP 
      has decreased and now it is prevalent in AIDS patients who do not receive HAART 
      or are unsuccessfully treated with persistent immune depression. Moreover, the 
      immunologic response to HAART has caused a PCP form which is included in the 
      immune restoration inflammatory syndrome (IRIS). As of late 2004, 75.5% of 
      patients cared for at Dr. Lucio Cordova Infectious Diseases Hospital were 
      receiving HAART. This study compares PCP clinical characteristics in patients 
      under the effect of HAART (n: 6) with those without antiretroviral therapy (n: 
      12). Among those with HAART, 83.3% (5/6) were without immunologic responses and 
      16.7% with virologic response. The median CD4 counts were low in both groups: 20 
      cells/mm(3) without HAART and 51 cells/mm(3) with HAART. There were no 
      differences in most of PCP characteristics, and no IRIS cases were observed. 
      HAART-receiving group had less severe disease and lower frequency of both, 
      complications and steroidal therapy prescription (P 0.023).
FAU - Bahamondes M, Laura
AU  - Bahamondes M L
AD  - Hospital de Enfermedades Infecciosas Dr. Lucio Cordova, Santiago, Chile. 
      bahamondeslaura@hotmail.com
FAU - Villar Z, M Jose
AU  - Villar Z MJ
FAU - Orellana C, Carolina
AU  - Orellana C C
FAU - Gonzalez R, Jimena
AU  - Gonzalez R J
FAU - Montenegro U, Cristian
AU  - Montenegro U C
LA  - spa
PT  - Comparative Study
PT  - Journal Article
TT  - Caracteristicas de la neumonia por Pneumocystis jiroveci en adultos con SIDA con 
      y sin terapia antiretroviral.
DEP - 20060804
PL  - Chile
TA  - Rev Chilena Infectol
JT  - Revista chilena de infectologia : organo oficial de la Sociedad Chilena de 
      Infectologia
JID - 9305754
RN  - 0 (Anti-HIV Agents)
RN  - 0 (Anti-Infective Agents)
RN  - 0 (Glucocorticoids)
SB  - IM
MH  - AIDS-Related Opportunistic Infections/*diagnosis/drug therapy/immunology
MH  - Adult
MH  - Anti-HIV Agents/*therapeutic use
MH  - Anti-Infective Agents/therapeutic use
MH  - *Antiretroviral Therapy, Highly Active
MH  - CD4 Lymphocyte Count
MH  - Cross-Sectional Studies
MH  - Female
MH  - Glucocorticoids/therapeutic use
MH  - Humans
MH  - Male
MH  - *Pneumocystis carinii
MH  - Pneumonia, Pneumocystis/*diagnosis/drug therapy/immunology
MH  - Severity of Illness Index
MH  - Viral Load
EDAT- 2006/08/10 09:00
MHDA- 2007/05/04 09:00
CRDT- 2006/08/10 09:00
PHST- 2006/08/10 09:00 [pubmed]
PHST- 2007/05/04 09:00 [medline]
PHST- 2006/08/10 09:00 [entrez]
AID - S0716-10182006000300003 [pii]
AID - 10.4067/s0716-10182006000300003 [doi]
PST - ppublish
SO  - Rev Chilena Infectol. 2006 Sep;23(3):215-9. doi: 10.4067/s0716-10182006000300003. 
      Epub 2006 Aug 4.