PMID- 1690179 OWN - NLM STAT- MEDLINE DCOM- 19900416 LR - 20190816 IS - 0020-5915 (Print) IS - 0020-5915 (Linking) VI - 91 IP - 1 DP - 1990 TI - Basophil releasability in human hydatidosis. PG - 111-2 AB - We studied immunoglobulin E (IgE)- and non-IgE-mediated releasability in basophils from 31 patients with hydatidosis. Histamine release to non-IgE-dependent stimuli did not differ significantly between normal individuals and patients with hydatidosis. On the contrary, an increased histamine liberation was obtained by challenging basophils from hydatid patients with anti-human IgE. It is concluded that Echinococcus granulosus infection induces an enhanced sensitivity of basophils to IgE-dependent stimuli. FAU - Aceti, A AU - Aceti A AD - Istituto di Clinica delle Malattie Tropicali e Infettive, Universita La Sapienza, Roma, Italia. FAU - Celestino, D AU - Celestino D FAU - Caferro, M AU - Caferro M FAU - Teggi, A AU - Teggi A FAU - Pennica, A AU - Pennica A FAU - Adriani, E AU - Adriani E FAU - Grilli, A AU - Grilli A FAU - Paparo, S AU - Paparo S FAU - Leri, O AU - Leri O FAU - De Rosa, F AU - De Rosa F AU - et al. LA - eng PT - Journal Article PL - Switzerland TA - Int Arch Allergy Appl Immunol JT - International archives of allergy and applied immunology JID - 0404561 RN - 0 (Antibodies, Anti-Idiotypic) RN - 0 (Antigens, Helminth) RN - 0 (anti-IgE antibodies) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Animals MH - Antibodies, Anti-Idiotypic/pharmacology MH - Antigens, Helminth/immunology MH - Basophils/*immunology MH - Echinococcosis/*immunology MH - Echinococcus/immunology MH - *Histamine Release MH - Humans MH - Immunoglobulin E/immunology/pharmacology EDAT- 1990/01/01 00:00 MHDA- 1990/01/01 00:01 CRDT- 1990/01/01 00:00 PHST- 1990/01/01 00:00 [pubmed] PHST- 1990/01/01 00:01 [medline] PHST- 1990/01/01 00:00 [entrez] AID - 10.1159/000235099 [doi] PST - ppublish SO - Int Arch Allergy Appl Immunol. 1990;91(1):111-2. doi: 10.1159/000235099.