PMID- 16903888
OWN - NLM
STAT- MEDLINE
DCOM- 20060828
LR  - 20061115
IS  - 1360-2276 (Print)
IS  - 1360-2276 (Linking)
VI  - 11
IP  - 8
DP  - 2006 Aug
TI  - Operational feasibility of lot quality assurance sampling (LQAS) as a tool in 
      routine process monitoring of filariasis control programmes.
PG  - 1256-63
AB  - Lot quality assurance sampling (LQAS) with two-stage sampling plan was applied 
      for rapid monitoring of coverage after every round of mass drug administration 
      (MDA). A Primary Health Centre (PHC) consisting of 29 villages in Thiruvannamalai 
      district, Tamil Nadu was selected as the study area. Two threshold levels of 
      coverage were used: threshold A (maximum: 60%; minimum: 40%) and threshold B 
      (maximum: 80%; minimum: 60%). Based on these thresholds, one sampling plan each 
      for A and B was derived with the necessary sample size and the number of 
      allowable defectives (i.e. defectives mean those who have not received the drug). 
      Using data generated through simple random sampling (SRSI) of 1,750 individuals 
      in the study area, LQAS was validated with the above two sampling plans for its 
      diagnostic and field applicability. Simultaneously, a household survey (SRSH) was 
      conducted for validation and cost-effectiveness analysis. Based on SRSH survey, 
      the estimated coverage was 93.5% (CI: 91.7-95.3%). LQAS with threshold A revealed 
      that by sampling a maximum of 14 individuals and by allowing four defectives, the 
      coverage was >or=60% in >90% of villages at the first stage. Similarly, with 
      threshold B by sampling a maximum of nine individuals and by allowing four 
      defectives, the coverage was >or=80% in >90% of villages at the first stage. 
      These analyses suggest that the sampling plan (14,4,52,25) of threshold A may be 
      adopted in MDA to assess if a minimum coverage of 60% has been achieved. However, 
      to achieve the goal of elimination, the sampling plan (9, 4, 42, 29) of threshold 
      B can identify villages in which the coverage is <80% so that remedial measures 
      can be taken. Cost-effectiveness analysis showed that both options of LQAS are 
      more cost-effective than SRSH to detect a village with a given level of coverage. 
      The cost per village was US dollars 76.18 under SRSH. The cost of LQAS was US 
      dollars 65.81 and 55.63 per village for thresholds A and B respectively. The 
      total financial cost of classifying a village correctly with the given threshold 
      level of LQAS could be reduced by 14% and 26% of the cost of conventional SRSH 
      method.
FAU - Vanamail, P
AU  - Vanamail P
AD  - Vector Control Research Centre, Indian Council of Medical Research, Pondicherry, 
      India.
FAU - Subramanian, S
AU  - Subramanian S
FAU - Srividya, A
AU  - Srividya A
FAU - Ravi, R
AU  - Ravi R
FAU - Krishnamoorthy, K
AU  - Krishnamoorthy K
FAU - Das, P K
AU  - Das PK
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Trop Med Int Health
JT  - Tropical medicine & international health : TM & IH
JID - 9610576
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Child
MH  - Child, Preschool
MH  - Cost-Benefit Analysis
MH  - Elephantiasis, Filarial/diagnosis/epidemiology/*prevention & control
MH  - Feasibility Studies
MH  - Humans
MH  - India/epidemiology
MH  - Middle Aged
MH  - Population Surveillance/methods
MH  - Quality Assurance, Health Care/economics/*methods
MH  - Rural Health
MH  - Sample Size
MH  - Sampling Studies
EDAT- 2006/08/15 09:00
MHDA- 2006/08/29 09:00
CRDT- 2006/08/15 09:00
PHST- 2006/08/15 09:00 [pubmed]
PHST- 2006/08/29 09:00 [medline]
PHST- 2006/08/15 09:00 [entrez]
AID - TMI1670 [pii]
AID - 10.1111/j.1365-3156.2006.01670.x [doi]
PST - ppublish
SO  - Trop Med Int Health. 2006 Aug;11(8):1256-63. doi: 
      10.1111/j.1365-3156.2006.01670.x.