PMID- 16903987
OWN - NLM
STAT- MEDLINE
DCOM- 20070403
LR  - 20060814
IS  - 1464-2662 (Print)
IS  - 1464-2662 (Linking)
VI  - 7
IP  - 6
DP  - 2006 Sep
TI  - Lymphoid pneumonitis as an immune reconstitution inflammatory syndrome in a 
      patient with CD4 cell recovery after HAART initiation.
PG  - 411-4
AB  - In the era of highly active antiretroviral therapy (HAART), immune reconstitution 
      inflammatory syndrome (IRIS) has come to present a significant clinical 
      challenge. Following the recovery of memory T cells, latent infections may lead 
      to clinical and laboratory deterioration despite immunological and virological 
      reconvalescence. However, many other forms of complications after induction of 
      HAART, which are not entirely understood, must be included in the entity of IRIS. 
      Here we report a case of a patient complaining of respiratory distress and fever 
      10 days after initiating HAART. Radiologically and clinically, his findings 
      mimicked Pneumocystis jiroveci pneumonia. However, no infectious agent could be 
      detected, and bronchoalveolary lavage showed a high cell count (90% lymphocytes 
      and 4% eosinophils) consistent with interstitial pneumonitis. He improved 
      dramatically after treatment with oral steroids.
FAU - Ingiliz, P
AU  - Ingiliz P
AD  - Department of Medicine I, University of Bonn, Bonn, Germany. p-ingiliz@web.de
FAU - Appenrodt, B
AU  - Appenrodt B
FAU - Gruenhage, F
AU  - Gruenhage F
FAU - Vogel, M
AU  - Vogel M
FAU - Tschampa, H
AU  - Tschampa H
FAU - Tasci, S
AU  - Tasci S
FAU - Rockstroh, J K
AU  - Rockstroh JK
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - HIV Med
JT  - HIV medicine
JID - 100897392
SB  - IM
MH  - Antiretroviral Therapy, Highly Active/*adverse effects
MH  - CD4-Positive T-Lymphocytes/immunology
MH  - HIV Infections/*drug therapy/immunology/virology
MH  - HIV-1/drug effects
MH  - Humans
MH  - Inflammation/*chemically induced/immunology/physiopathology
MH  - Lung Diseases, Interstitial/*chemically induced/immunology/physiopathology
MH  - Lymphoid Tissue/*immunology/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - Syndrome
EDAT- 2006/08/15 09:00
MHDA- 2007/04/04 09:00
CRDT- 2006/08/15 09:00
PHST- 2006/08/15 09:00 [pubmed]
PHST- 2007/04/04 09:00 [medline]
PHST- 2006/08/15 09:00 [entrez]
AID - HIV389 [pii]
AID - 10.1111/j.1468-1293.2006.00389.x [doi]
PST - ppublish
SO  - HIV Med. 2006 Sep;7(6):411-4. doi: 10.1111/j.1468-1293.2006.00389.x.