PMID- 16909795
OWN - NLM
STAT- MEDLINE
DCOM- 20070103
LR  - 20060816
IS  - 0033-2100 (Print)
IS  - 0033-2100 (Linking)
VI  - 60 Suppl 1
DP  - 2006
TI  - [Infectious agents in the pathogenesis of multiple sclerosis].
PG  - 160-5
AB  - Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous 
      system (CNS) of a still unknown etiology. Genetic factors, environmental agents 
      and an autoimmune response may play an important role in the pathogenesis of MS. 
      In the paper the current opinion on the role of infectious agents in the 
      pathogenesis of MS is presented. The results of epidemiological and serological 
      studies are discussed as well as the results of viral isolation attempts and the 
      search for virus structures in the CNS of MS patients. The most important 
      findings in the field e.g. a potential role of Epstein-Barr virus (EBV), human 
      herpesvirus 6 (HHV-6) and bacteria Chlamydia pneumoniae in MS are presented. 
      Postulated mechanisms of virus-induced demyelination are also described.
FAU - Szczucinski, Adam
AU  - Szczucinski A
AD  - Zaklad Neuroimmunologii Klinicznej Katedry Neurologii, Akademii Medycznej w 
      Poznaniu.
FAU - Losy, Jacek
AU  - Losy J
LA  - pol
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Czynniki infekcyjne w patogenezie stwardnienia rozsianego.
PL  - Poland
TA  - Przegl Epidemiol
JT  - Przeglad epidemiologiczny
JID - 0413725
SB  - IM
MH  - Chlamydia Infections/*complications
MH  - Chlamydophila pneumoniae/pathogenicity
MH  - Herpesviridae Infections/*complications
MH  - Herpesvirus 4, Human/pathogenicity
MH  - Herpesvirus 6, Human/pathogenicity
MH  - Humans
MH  - Multiple Sclerosis/epidemiology/*microbiology/*virology
RF  - 17
EDAT- 2006/08/17 09:00
MHDA- 2007/01/04 09:00
CRDT- 2006/08/17 09:00
PHST- 2006/08/17 09:00 [pubmed]
PHST- 2007/01/04 09:00 [medline]
PHST- 2006/08/17 09:00 [entrez]
PST - ppublish
SO  - Przegl Epidemiol. 2006;60 Suppl 1:160-5.