PMID- 1691899
OWN - NLM
STAT- MEDLINE
DCOM- 19900531
LR  - 20190902
IS  - 0193-1091 (Print)
IS  - 0193-1091 (Linking)
VI  - 12
IP  - 2
DP  - 1990 Apr
TI  - Cell differentiation in benign cutaneous fibrous histiocytomas. An 
      immunohistochemical study with antibodies to histiomonocytic cells and 
      intermediate filament proteins.
PG  - 134-40
AB  - Seven benign cutaneous fibrous histiocytomas (BFHs) were investigated 
      immunohistochemically by using a panel of antibodies to histiomonocytic cells and 
      intermediate filament proteins. Immunoreactivity with antimacrophage antibodies 
      was observed in all tumors in a significant but varying proportion of the tumor 
      cells. All tumors were also positive for vimentin. In addition, two of the BFHs 
      were positive for cytokeratin and one for desmin. The results suggest that BFHs 
      either display a true histiomonocytic trait or, alternatively, contain a 
      prominent histiomonocytic infiltration. Some BFHs may be related to smooth muscle 
      cells as indicated by desmin positivity. The occasional occurrence of cytokeratin 
      in BFHs could also be explained by smooth muscle cell differentiation.
FAU - Soini, Y
AU  - Soini Y
AD  - Department of Pathology, University of Oulu, Finland.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Dermatopathol
JT  - The American Journal of dermatopathology
JID - 7911005
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Desmin)
RN  - 0 (Intermediate Filament Proteins)
RN  - 0 (Vimentin)
RN  - 68238-35-7 (Keratins)
SB  - IM
MH  - Adult
MH  - Antibodies, Monoclonal
MH  - Cell Differentiation
MH  - Desmin/metabolism
MH  - Female
MH  - Histiocytoma, Benign Fibrous/metabolism/*pathology
MH  - Humans
MH  - Immunohistochemistry
MH  - Intermediate Filament Proteins/*metabolism
MH  - Keratins/metabolism
MH  - Male
MH  - Middle Aged
MH  - Monocytes/*metabolism
MH  - Skin Neoplasms/metabolism/*pathology
MH  - Vimentin/metabolism
EDAT- 1990/04/01 00:00
MHDA- 1990/04/01 00:01
CRDT- 1990/04/01 00:00
PHST- 1990/04/01 00:00 [pubmed]
PHST- 1990/04/01 00:01 [medline]
PHST- 1990/04/01 00:00 [entrez]
AID - 10.1097/00000372-199004000-00003 [doi]
PST - ppublish
SO  - Am J Dermatopathol. 1990 Apr;12(2):134-40. doi: 10.1097/00000372-199004000-00003.