PMID- 16920497
OWN - NLM
STAT- MEDLINE
DCOM- 20061227
LR  - 20161124
IS  - 0171-2985 (Print)
IS  - 0171-2985 (Linking)
VI  - 211
IP  - 6-8
DP  - 2006
TI  - Non-invasive imaging of dendritic cell migration in vivo.
PG  - 587-97
AB  - Dendritic cells (DCs) play important roles in the initiation of adaptive immune 
      responses. The transport of antigen from the infection site to the draining lymph 
      node by DCs is a crucial component in this process. Accordingly, 
      immunotherapeutic applications of in vitro-generated DCs require reliable methods 
      experimentally in mice and clinically in patients to monitor the efficiency of 
      their successful lymph node homing after injection. Recent developments of new 
      methods to follow DC migration by non-invasive imaging modalities such as 
      scintigraphy, PET, MRI, or bioluminescence imaging, have gained attraction 
      because of their potential clinical applicability. The current state of the 
      literature and a comparative evaluation of the methods are reported in this 
      review.
FAU - Baumjohann, Dirk
AU  - Baumjohann D
AD  - Department of Dermatology, University Hospital Erlangen, Hartmannstr. 14, 91052 
      Erlangen, Germany.
FAU - Lutz, Manfred B
AU  - Lutz MB
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20060703
PL  - Netherlands
TA  - Immunobiology
JT  - Immunobiology
JID - 8002742
SB  - IM
MH  - Animals
MH  - Cell Movement/*physiology
MH  - Dendritic Cells/diagnostic imaging/*physiology
MH  - *Diagnostic Imaging
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Positron-Emission Tomography
RF  - 95
EDAT- 2006/08/22 09:00
MHDA- 2006/12/28 09:00
CRDT- 2006/08/22 09:00
PHST- 2006/08/22 09:00 [pubmed]
PHST- 2006/12/28 09:00 [medline]
PHST- 2006/08/22 09:00 [entrez]
AID - S0171-2985(06)00068-4 [pii]
AID - 10.1016/j.imbio.2006.05.011 [doi]
PST - ppublish
SO  - Immunobiology. 2006;211(6-8):587-97. doi: 10.1016/j.imbio.2006.05.011. Epub 2006 
      Jul 3.