PMID- 16921576
OWN - NLM
STAT- MEDLINE
DCOM- 20070829
LR  - 20060828
IS  - 1076-5174 (Print)
IS  - 1076-5174 (Linking)
VI  - 41
IP  - 8
DP  - 2006 Aug
TI  - DNA analysis by mass spectrometry-past, present and future.
PG  - 981-95
AB  - The analysis of deoxyribose nucleic acid (DNA) by mass spectrometry (MS) has 
      evolved to where it can be used to analyze most known types of DNA and ribose 
      nucleic acid (RNA) situations. It can efficiently deal with the analysis of DNA 
      polymorphisms, sequences, haplotypes, human leukocyte antigen (HLA) typing, DNA 
      methylation and RNA expression. Implementations of MS for these forms of DNA 
      analyses are reviewed. The use of DNA analysis by MS is compared with competing 
      technologies. Finally, an overview is given of worthwhile applications where the 
      know-how gained so far could be used for future developments.
CI  - Copyright 2006 John Wiley & Sons, Ltd.
FAU - Tost, Jorg
AU  - Tost J
AD  - Centre National de Genotypage, Batiment G2, 2 rue Gaston Cremieux, CP 5721, 91057 
      Evry Cedex, France.
FAU - Gut, Ivo Glynne
AU  - Gut IG
LA  - eng
PT  - Historical Article
PT  - Journal Article
PT  - Review
PL  - England
TA  - J Mass Spectrom
JT  - Journal of mass spectrometry : JMS
JID - 9504818
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Animals
MH  - DNA/*analysis
MH  - DNA Methylation
MH  - Gene Expression
MH  - Genomics
MH  - Genotype
MH  - History, 20th Century
MH  - History, 21st Century
MH  - Humans
MH  - *Mass Spectrometry/history/trends
MH  - Polymorphism, Single Nucleotide
MH  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/history/trends
RF  - 120
EDAT- 2006/08/22 09:00
MHDA- 2007/08/30 09:00
CRDT- 2006/08/22 09:00
PHST- 2006/08/22 09:00 [pubmed]
PHST- 2007/08/30 09:00 [medline]
PHST- 2006/08/22 09:00 [entrez]
AID - 10.1002/jms.1096 [doi]
PST - ppublish
SO  - J Mass Spectrom. 2006 Aug;41(8):981-95. doi: 10.1002/jms.1096.