PMID- 16928333
OWN - NLM
STAT- MEDLINE
DCOM- 20071218
LR  - 20161018
IS  - 1009-2137 (Print)
IS  - 1009-2137 (Linking)
VI  - 14
IP  - 4
DP  - 2006 Aug
TI  - [Bone marrow necrosis as an initial manifestation of Philadelphia chromosome and 
      myeloid antigens positive B acute lymphoblastic leukemia--a case report].
PG  - 832-4
AB  - Many diseases cause bone marrow necrosis (BMN), especially lymphocytic leukemia. 
      To explore the complexity of the pathogenesis and pathology of BMN and understand 
      the multiplicity of clinical features, a case of Philadelphia chromosome positive 
      (Ph+) B acute lymphoblastic leukemia (ALL) expressing myeloid antigens was 
      reported. The results indicated that the clinical features of this case were 
      complicated and multiplex, the diagnosis was confirmed by using bone marrow smear 
      and biopsy, immunophenotype analysis, conventional cytogenetics and fluorescence 
      in situ hybridization (FISH), the prognosis of patients improved by active 
      treatment for primary disease. In conclusion, the Ph+ B ALL expressing myeloid 
      antigen with BMN is very rare, its diagnosis should be confirmed by using 
      multiple methods, and the active treatments should be performed.
FAU - Lin, Ru-Feng
AU  - Lin RF
AD  - Department of Hematology, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing 210029, China.
FAU - Li, Jian-Yong
AU  - Li JY
FAU - Lu, Hua
AU  - Lu H
FAU - Wu, Yu-Jie
AU  - Wu YJ
FAU - Qiu, Hai-Rong
AU  - Qiu HR
FAU - Xiao, Bing
AU  - Xiao B
FAU - Zhang, Jian-Fu
AU  - Zhang JF
FAU - Yang, Hui
AU  - Yang H
LA  - chi
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhongguo Shi Yan Xue Ye Xue Za Zhi
JT  - Zhongguo shi yan xue ye xue za zhi
JID - 101084424
RN  - 0 (Antigens, Neoplasm)
SB  - IM
MH  - Adult
MH  - Antigens, Neoplasm/*blood
MH  - Bone Marrow/*pathology
MH  - Bone Marrow Diseases/etiology
MH  - Burkitt Lymphoma/complications/*genetics/immunology
MH  - Female
MH  - Humans
MH  - Immunophenotyping
MH  - Necrosis/etiology
MH  - *Philadelphia Chromosome
EDAT- 2006/08/25 09:00
MHDA- 2007/12/19 09:00
CRDT- 2006/08/25 09:00
PHST- 2006/08/25 09:00 [pubmed]
PHST- 2007/12/19 09:00 [medline]
PHST- 2006/08/25 09:00 [entrez]
AID - 1009-2137(2006)04-0832-03 [pii]
PST - ppublish
SO  - Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2006 Aug;14(4):832-4.