PMID- 16944031
OWN - NLM
STAT- MEDLINE
DCOM- 20070927
LR  - 20161124
IS  - 0942-8925 (Print)
IS  - 0942-8925 (Linking)
VI  - 32
IP  - 1
DP  - 2007 Jan-Feb
TI  - Small cystic lesions of the pancreas: clinical significance and findings at 
      follow-up.
PG  - 119-25
AB  - BACKGROUND: Our purpose was to correlate the imaging findings of small cystic 
      pancreatic lesions to the incidence of growth on follow-up imaging and their 
      pathologic diagnoses. METHODS: CT images for 159 patients with cystic pancreatic 
      lesions were retrospectively evaluated and lesions were assessed for size, 
      number, connection to the main pancreatic duct (MPD), MPD dilatation, and any 
      presence of loculation, wall irregularity, thick septations, or solid components. 
      A total of 86 patients had follow-up imaging with time periods of less than 6 
      months (n = 21), 6-12 months (n = 22), 1-2 years (n = 14), and greater than 2 
      years (n = 29). Lesion histology was available in 20 patients. RESULTS: Lesions 
      with pathologic correlation proved to be: side branch intraductal papillary 
      mucinous neoplasm or tumor (IPMT) (n = 5), combined type IPMT (n = 4), 
      nonmucinous cyst (n = 4), chronic pancreatitis (n = 2), and reactive atypia with 
      nonmucinous fluid (n = 1), combined type IMPT with foci of adenocarcinoma (n = 
      1), mucinous adenocarcinoma (n = 2), and nonmucinous adenocarcinoma (n = 1). 
      Lesions with solid components were significantly more likely to grow and be 
      malignant (P < 0.05). The presence of MPD dilatation was more common in patients 
      with combined type IPMTs or malignancies. No other factors were predictive of 
      malignancy. CONCLUSIONS: Solid components are predictive of malignancy, and MPD 
      dilatation should prompt consideration of surgery. Other cystic lesions can be 
      followed.
FAU - Kirkpatrick, Iain D C
AU  - Kirkpatrick ID
AD  - Diagnostic Radiology, University of Manitoba, Winnipeg, Manitoba, Canada. 
      kirkpati@cc.umanitoba.ca
FAU - Desser, Terry S
AU  - Desser TS
FAU - Nino-Murcia, Matilde
AU  - Nino-Murcia M
FAU - Jeffrey, R Brooke
AU  - Jeffrey RB
LA  - eng
PT  - Journal Article
DEP - 20060831
PL  - United States
TA  - Abdom Imaging
JT  - Abdominal imaging
JID - 9303672
SB  - IM
MH  - Adenocarcinoma/diagnostic imaging
MH  - Adenocarcinoma, Mucinous/diagnostic imaging
MH  - Adenocarcinoma, Papillary/diagnostic imaging
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cell Transformation, Neoplastic
MH  - Dilatation, Pathologic/diagnostic imaging
MH  - Disease Progression
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Male
MH  - Middle Aged
MH  - Pancreatic Cyst/*diagnostic imaging/pathology/physiopathology
MH  - Pancreatic Ducts/diagnostic imaging
MH  - Pancreatitis, Chronic/diagnostic imaging
MH  - Retrospective Studies
MH  - *Tomography, X-Ray Computed
EDAT- 2006/09/01 09:00
MHDA- 2007/09/28 09:00
CRDT- 2006/09/01 09:00
PHST- 2005/07/03 00:00 [received]
PHST- 2005/08/25 00:00 [accepted]
PHST- 2006/09/01 09:00 [pubmed]
PHST- 2007/09/28 09:00 [medline]
PHST- 2006/09/01 09:00 [entrez]
AID - 10.1007/s00261-006-9080-5 [doi]
PST - ppublish
SO  - Abdom Imaging. 2007 Jan-Feb;32(1):119-25. doi: 10.1007/s00261-006-9080-5. Epub 
      2006 Aug 31.