PMID- 16954660
OWN - NLM
STAT- MEDLINE
DCOM- 20060918
LR  - 20220316
IS  - 1424-859X (Electronic)
IS  - 1424-8581 (Linking)
VI  - 114
IP  - 3-4
DP  - 2006
TI  - Multicolor fluorescence in situ hybridization (FISH) applied to FISH-banding.
PG  - 240-4
AB  - During the last decade not only multicolor fluorescence in situ hybridization 
      (FISH) using whole chromosome paints as probes, but also numerous chromosome 
      banding techniques based on FISH have been developed for the human and for the 
      murine genome. This review focuses on such FISH-banding techniques, which were 
      recently defined as 'any kind of FISH technique, which provide the possibility to 
      characterize simultaneously several chromosomal subregions smaller than a 
      chromosome arm. FISH-banding methods fitting that definition may have quite 
      different characteristics, but share the ability to produce a DNA-specific 
      chromosomal banding'. While the standard chromosome banding techniques like GTG 
      lead to a protein-related black and white banding pattern, FISH-banding 
      techniques are DNA-specific, more colorful and, thus, more informative. For some, 
      even high-resolution FISH-banding techniques the development is complete and they 
      can be used for whole genome hybridizations in one step. Other FISH-banding 
      methods are only available for selected chromosomes and/or are still under 
      development. FISH-banding methods have successfully been applied in research in 
      evolution- and radiation-biology, as well as in studies on the nuclear 
      architecture. Moreover, their suitability for diagnostic purposes has been proven 
      in prenatal, postnatal and tumor cytogenetics, indicating that they are an 
      important tool with the potential to partly replace the conventional banding 
      techniques in the future.
CI  - Copyright 2006 S. Karger AG, Basel.
FAU - Liehr, T
AU  - Liehr T
AD  - Institute of Human Genetics and Anthropology, Friedrich Schiller University, 
      Jena, Germany. i8lith@mti.uni-jena.de
FAU - Starke, H
AU  - Starke H
FAU - Heller, A
AU  - Heller A
FAU - Kosyakova, N
AU  - Kosyakova N
FAU - Mrasek, K
AU  - Mrasek K
FAU - Gross, M
AU  - Gross M
FAU - Karst, C
AU  - Karst C
FAU - Steinhaeuser, U
AU  - Steinhaeuser U
FAU - Hunstig, F
AU  - Hunstig F
FAU - Fickelscher, I
AU  - Fickelscher I
FAU - Kuechler, A
AU  - Kuechler A
FAU - Trifonov, V
AU  - Trifonov V
FAU - Romanenko, S A
AU  - Romanenko SA
FAU - Weise, A
AU  - Weise A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Switzerland
TA  - Cytogenet Genome Res
JT  - Cytogenetic and genome research
JID - 101142708
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Bone Marrow Cells/pathology
MH  - *Chromosome Banding
MH  - Chromosome Painting/methods
MH  - DNA/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Leukemia, Myeloid, Acute/genetics/pathology
MH  - Male
MH  - Metaphase
RF  - 40
EDAT- 2006/09/07 09:00
MHDA- 2006/09/19 09:00
CRDT- 2006/09/07 09:00
PHST- 2005/06/24 00:00 [received]
PHST- 2005/09/13 00:00 [accepted]
PHST- 2006/09/07 09:00 [pubmed]
PHST- 2006/09/19 09:00 [medline]
PHST- 2006/09/07 09:00 [entrez]
AID - 94207 [pii]
AID - 10.1159/000094207 [doi]
PST - ppublish
SO  - Cytogenet Genome Res. 2006;114(3-4):240-4. doi: 10.1159/000094207.