PMID- 16954664
OWN - NLM
STAT- MEDLINE
DCOM- 20060918
LR  - 20061115
IS  - 1424-859X (Electronic)
IS  - 1424-8581 (Linking)
VI  - 114
IP  - 3-4
DP  - 2006
TI  - Multicolor PRINS and multicolor PNA.
PG  - 263-9
AB  - Both PRimed IN Situ (PRINS) and Peptide Nucleic Acid (PNA) technologies have 
      emerged as research techniques, but they have quickly evolved to applications in 
      biological diagnosis assays. The two procedures now constitute efficient 
      alternatives to the conventional fluorescence in situ hybridization (FISH) 
      procedure for in situ chromosome identification and aneuploidy detection. They 
      present several advantages (specificity, speed, discriminating ability) that make 
      them very attractive for a number of cytogenetic purposes. Multicolor PRINS and 
      PNA protocols have been described for the specific identification of human 
      chromosomes. Various applications have already been developed in human genetics 
      and new adaptations are ongoing.
CI  - Copyright 2006 S. Karger AG, Basel.
FAU - Pellestor, F
AU  - Pellestor F
AD  - CNRS UPR 1142, Institute of Human Genetics, Montpellier, France. 
      Franck.Pellestor@igh.cnrs.fr
FAU - Paulasova, P
AU  - Paulasova P
FAU - Andreo, B
AU  - Andreo B
FAU - Lefort, G
AU  - Lefort G
FAU - Hamamah, S
AU  - Hamamah S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Cytogenet Genome Res
JT  - Cytogenetic and genome research
JID - 101142708
RN  - 0 (DNA Primers)
RN  - 0 (Peptide Nucleic Acids)
SB  - IM
MH  - Chromosome Mapping/*methods
MH  - Chromosome Painting/methods
MH  - *Chromosomes, Human
MH  - Color
MH  - DNA Primers
MH  - Humans
MH  - In Situ Hybridization/methods
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Peptide Nucleic Acids/*genetics
EDAT- 2006/09/07 09:00
MHDA- 2006/09/19 09:00
CRDT- 2006/09/07 09:00
PHST- 2005/11/03 00:00 [received]
PHST- 2005/12/07 00:00 [accepted]
PHST- 2006/09/07 09:00 [pubmed]
PHST- 2006/09/19 09:00 [medline]
PHST- 2006/09/07 09:00 [entrez]
AID - 94211 [pii]
AID - 10.1159/000094211 [doi]
PST - ppublish
SO  - Cytogenet Genome Res. 2006;114(3-4):263-9. doi: 10.1159/000094211.