PMID- 1695525
OWN - NLM
STAT- MEDLINE
DCOM- 19900827
LR  - 20190719
IS  - 0306-5456 (Print)
IS  - 0306-5456 (Linking)
VI  - 97
IP  - 5
DP  - 1990 May
TI  - Uterine artery Doppler in the investigation of pregnancies with raised maternal 
      serum alpha-fetoprotein.
PG  - 431-5
AB  - Uterine artery flow velocity waveforms (FVW) were obtained prospectively by 
      continuous wave Doppler at 18-22 weeks gestation from 98 women with an 
      unexplained elevation in maternal serum alpha-fetoprotein (MSAFP). A notch in 
      either the left or right uterine artery FVW was present in 18 pregnancies of 
      which seven resulted in perinatal death and six in the birth of very immature 
      and/or severely growth retarded babies. Conversely, in 66 of 80 pregnancies the 
      absence of a notch was associated with the livebirth of an infant beyond 32 weeks 
      gestation, with a birthweight above the 5th centile. It is suggested that the 
      presence of a notch in the uterine artery FVW is a good predictor of poor 
      perinatal outcome.
FAU - Aristidou, A
AU  - Aristidou A
AD  - Harris Birthright Research Centre for Fetal Medicine, King's College School of 
      Medicine and Dentistry, London.
FAU - Van den Hof, M C
AU  - Van den Hof MC
FAU - Campbell, S
AU  - Campbell S
FAU - Nicolaides, K
AU  - Nicolaides K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Br J Obstet Gynaecol
JT  - British journal of obstetrics and gynaecology
JID - 7503752
RN  - 0 (alpha-Fetoproteins)
SB  - IM
MH  - Blood Flow Velocity
MH  - Female
MH  - Fetal Death
MH  - Fetal Growth Retardation/physiopathology
MH  - Gestational Age
MH  - Humans
MH  - Infant, Newborn
MH  - Pregnancy
MH  - Pregnancy Complications/*blood/physiopathology
MH  - Pregnancy Outcome
MH  - Prospective Studies
MH  - Ultrasonography
MH  - Uterus/*blood supply
MH  - Vascular Resistance/physiology
MH  - alpha-Fetoproteins/*analysis
EDAT- 1990/05/01 00:00
MHDA- 1990/05/01 00:01
CRDT- 1990/05/01 00:00
PHST- 1990/05/01 00:00 [pubmed]
PHST- 1990/05/01 00:01 [medline]
PHST- 1990/05/01 00:00 [entrez]
AID - 10.1111/j.1471-0528.1990.tb01831.x [doi]
PST - ppublish
SO  - Br J Obstet Gynaecol. 1990 May;97(5):431-5. doi: 
      10.1111/j.1471-0528.1990.tb01831.x.