PMID- 16956586
OWN - NLM
STAT- MEDLINE
DCOM- 20070123
LR  - 20181113
IS  - 0006-8993 (Print)
IS  - 0006-8993 (Linking)
VI  - 1118
IP  - 1
DP  - 2006 Nov 6
TI  - The effects of attentional load on auditory ERPs recorded from human cortex.
PG  - 94-105
AB  - Responses to acoustic input were recorded from human temporal cortex using 
      subdural electrodes in order to investigate in greater anatomical detail how 
      attentional load modulates exogenous auditory responses. Four patient-volunteers 
      performed a dichotic listening task in which they listened for rare frequency 
      deviants in a series of tones presented to both ears at interstimulus intervals 
      (ISIs) of 400, 800, and 2000 ms. Across all ISIs, stimuli presented contralateral 
      to electrode location produced the strongest deflections in the averaged ERP at 
      approximately 90 and 170 ms post-stimulus on average (labeled N90stg and 
      P170stg). Maximal recording sites for these peaks most often occurred over the 
      Sylvian fissure or the upper bank of the posterior superior temporal gyrus. 
      Neither ISI nor selective attention exhibited substantial effects on peak 
      latencies. However, as presentation rates increased (decreasing ISI), overall 
      averaged event-related potential (ERP) amplitudes declined significantly, while 
      attending to the contralateral stimulus significantly increased both the N90stg 
      and P170stg peaks for most patients. This effect of attention increased with 
      decreasing ISI for both components most clearly in the difference between the 
      grand-average ERPs for attending to vs. ignoring the contralateral stimulus, and 
      even more dramatically in the percentage ratio of that difference over the mean 
      peak amplitude. This amplifying effect of attention with increasing load, along 
      with its anatomical location, suggests that attention can enhance exogenous 
      sources in auditory cortex.
FAU - Neelon, Michael F
AU  - Neelon MF
AD  - Department of Psychology, University of North Carolina, Asheville, NC, USA.
FAU - Williams, Justin
AU  - Williams J
FAU - Garell, P Charles
AU  - Garell PC
LA  - eng
GR  - L30 DC006388-01/DC/NIDCD NIH HHS/United States
GR  - K23 DC006415-03/DC/NIDCD NIH HHS/United States
GR  - K23 DC006415-02/DC/NIDCD NIH HHS/United States
GR  - K23 DC006415-01/DC/NIDCD NIH HHS/United States
GR  - 5K23DC006415/DC/NIDCD NIH HHS/United States
GR  - K23 DC006415/DC/NIDCD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20060907
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
SB  - IM
MH  - Acoustic Stimulation
MH  - Adult
MH  - Attention/*physiology
MH  - Auditory Cortex/*physiology
MH  - Auditory Pathways/physiology
MH  - Auditory Perception/*physiology
MH  - Electroencephalography
MH  - Evoked Potentials/*physiology
MH  - Evoked Potentials, Auditory/*physiology
MH  - Female
MH  - Functional Laterality/physiology
MH  - Humans
MH  - Male
MH  - Reaction Time/physiology
MH  - Time Factors
PMC - PMC2577293
MID - NIHMS13671
EDAT- 2006/09/08 09:00
MHDA- 2007/01/24 09:00
PMCR- 2008/11/03
CRDT- 2006/09/08 09:00
PHST- 2005/11/17 00:00 [received]
PHST- 2006/06/01 00:00 [revised]
PHST- 2006/08/04 00:00 [accepted]
PHST- 2006/09/08 09:00 [pubmed]
PHST- 2007/01/24 09:00 [medline]
PHST- 2006/09/08 09:00 [entrez]
PHST- 2008/11/03 00:00 [pmc-release]
AID - S0006-8993(06)02360-2 [pii]
AID - 10.1016/j.brainres.2006.08.006 [doi]
PST - ppublish
SO  - Brain Res. 2006 Nov 6;1118(1):94-105. doi: 10.1016/j.brainres.2006.08.006. Epub 
      2006 Sep 7.