PMID- 16973327
OWN - NLM
STAT- MEDLINE
DCOM- 20061213
LR  - 20061030
IS  - 0753-3322 (Print)
IS  - 0753-3322 (Linking)
VI  - 60
IP  - 9
DP  - 2006 Nov
TI  - Large needle percutaneous aspiration biopsy of the testicle in men with 
      nonobstructive azoospermia: technical performance.
PG  - 557-60
AB  - The aim of this study was to relate retrospectively in 215 percutaneous large 
      needle aspiration biopsy (LNAB) of the testicles the number of seminiferous 
      tubules (ST) per testicular biopsy, from differently sized testicles, to the size 
      of the needle used in order to obtain information useful for selecting the needle 
      size according to the testicular size. Clinical, ultrasonographic and pathologic 
      data of 134 patients with nonobstructive azoospermia examined with LNAB were 
      retrospectively analyzed. One hundred and sixty-three testicles with volume>or=10 
      ml, 39<10 ml and>or=6 ml, 13<6 ml underwent 215 LNABs. In the larger testicle 
      group the prevalence of adequate biopsies (ST>/=20) varied from 83% to 50% with a 
      statistically significant difference among the needle groups (P=0.028) and being 
      83% in the biopsies with the 18 gauge (g.) needle. The mean number of ST obtained 
      with the 18 g. needle was significantly higher than that obtained with the other 
      needles (P=0.000). In the medium volume testicle group the adequate biopsy 
      incidence varied from 20% to 83.3% with statistical significance among the 
      various needle groups (P=0.042) being 83.3% in the biopsies with the 22 g. 
      needle. In the smaller testicle group the mean number of ST obtained with the 22 
      g. needle was significantly higher than with the 20 g. needle (71 versus 25, 
      P=0.011). In the patients with nonobstructive azoospermia, the 18 g. needle 
      seemed to offer the best performance in the larger testicles, while in the medium 
      and lower sized testicles the smaller 22 g. needle gave results comparable to or 
      slightly better than the other larger needles.
FAU - Carpi, Angelo
AU  - Carpi A
AD  - Department of Reproduction and Aging, University of Pisa, Pisa, Italy. 
      a.carpi@med.unipi.it
FAU - Fabris, Fabrizio Giuseppe Menchini
AU  - Fabris FG
FAU - Todeschini, Giuseppe
AU  - Todeschini G
FAU - Nardini, Vincenzo
AU  - Nardini V
FAU - Toldin, Maria Rosaria Parisen
AU  - Toldin MR
FAU - Nicolini, Andrea
AU  - Nicolini A
FAU - Rossi, Giuseppe
AU  - Rossi G
LA  - eng
PT  - Journal Article
DEP - 20060828
PL  - France
TA  - Biomed Pharmacother
JT  - Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
JID - 8213295
SB  - IM
MH  - Adult
MH  - Azoospermia/*pathology
MH  - Biopsy, Needle/*methods
MH  - Humans
MH  - Male
MH  - Retrospective Studies
MH  - Seminiferous Tubules/pathology
MH  - Testis/*pathology
EDAT- 2006/09/16 09:00
MHDA- 2006/12/14 09:00
CRDT- 2006/09/16 09:00
PHST- 2006/07/03 00:00 [received]
PHST- 2006/07/28 00:00 [accepted]
PHST- 2006/09/16 09:00 [pubmed]
PHST- 2006/12/14 09:00 [medline]
PHST- 2006/09/16 09:00 [entrez]
AID - S0753-3322(06)00251-4 [pii]
AID - 10.1016/j.biopha.2006.07.088 [doi]
PST - ppublish
SO  - Biomed Pharmacother. 2006 Nov;60(9):557-60. doi: 10.1016/j.biopha.2006.07.088. 
      Epub 2006 Aug 28.