PMID- 16979279
OWN - NLM
STAT- MEDLINE
DCOM- 20070730
LR  - 20061218
IS  - 0300-5712 (Print)
IS  - 0300-5712 (Linking)
VI  - 35
IP  - 1
DP  - 2007 Jan
TI  - Comparative evaluation of the peri-implant bone tissue mineral density around 
      unloaded titanium dental implants.
PG  - 84-92
AB  - OBJECTIVE: The mechanical properties of bone are greatly influenced by the 
      percentages of organic and mineral constituents. Nevertheless, the information 
      about the mineral content on a microscopic scale in peri-implant bone is scarce. 
      The aim of this work was to analyze the bone mineral density of peri-implant bone 
      under different techniques. DESIGN: Five unloaded titanium dental implants with a 
      micro-structured surface (three XiVE plus and two Frialit 2, DENTSPLY-Friadent, 
      Mannheim, Germany) were retrieved from the mandible of five patients after a 
      6-month period. scanning electron microscopy with backscattered electron signal 
      (BSE), light microscopy (LM) with a double staining technique, fluorescence 
      microscopy and confocal laser microscopy were used for measuring microscopic 
      mineral content variations in peri-implant bone. Histomorphometry and image 
      intensity (grey level) were evaluated using a software package for image 
      analysis. RESULTS: The low mineral density index (LMDI) for LM was of 29.2+/-3.1 
      (mean+/-S.D.), while the high mineral density index (HMDI) was of 88.2+/-3.6 
      (mean+/-S.D.). The one-way ANOVA analysis showed a significant difference 
      (P<0.001) among the groups. The pairwise Holm-Sidak test identified the 
      differences among HMDI indexes for both LM and SEM values and also for 
      cross-evaluation of the LMDI and HMDI values. The comparison between LMDI indexes 
      for both SEM and LM did not show any significance. The fluorescence microscopy 
      analysis showed clearly the difference between old (high mineralized) and new 
      (low mineralized) bone tissue near the implant surface. Under confocal laser 
      microscopy the same sections showed the area of bone modelling closest to implant 
      surface. CONCLUSION: In this study it was found that bone around unloaded 
      implants showed a low mineral density index under all the investigation methods 
      used. It was also found that the conventional LM technique with the double 
      staining method was able to intensely stain the bone area with a low mineral 
      content.
FAU - Traini, Tonino
AU  - Traini T
AD  - Dental School, University of Chieti-Pescara, Via F. Sciucchi 63, 66100 Chieti, 
      Italy.
FAU - Degidi, Marco
AU  - Degidi M
FAU - Iezzi, Giovanna
AU  - Iezzi G
FAU - Artese, Luciano
AU  - Artese L
FAU - Piattelli, Adriano
AU  - Piattelli A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20060918
PL  - England
TA  - J Dent
JT  - Journal of dentistry
JID - 0354422
RN  - 0 (Dental Implants)
SB  - IM
MH  - Analysis of Variance
MH  - *Bone Density
MH  - *Dental Implantation, Endosseous
MH  - *Dental Implants
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Tooth Socket/*chemistry
MH  - Weight-Bearing
EDAT- 2006/09/19 09:00
MHDA- 2007/07/31 09:00
CRDT- 2006/09/19 09:00
PHST- 2005/08/11 00:00 [received]
PHST- 2006/05/08 00:00 [revised]
PHST- 2006/05/15 00:00 [accepted]
PHST- 2006/09/19 09:00 [pubmed]
PHST- 2007/07/31 09:00 [medline]
PHST- 2006/09/19 09:00 [entrez]
AID - S0300-5712(06)00097-2 [pii]
AID - 10.1016/j.jdent.2006.05.002 [doi]
PST - ppublish
SO  - J Dent. 2007 Jan;35(1):84-92. doi: 10.1016/j.jdent.2006.05.002. Epub 2006 Sep 18.