PMID- 17017153
OWN - NLM
STAT- MEDLINE
DCOM- 20100707
LR  - 20161124
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 24
IP  - 4
DP  - 2006 Jul
TI  - [Determination of three nitroimidazole residues in royal jelly by high 
      performance liquid chromatography-tandem mass spectrometry].
PG  - 331-4
AB  - A method for analysis of trace metronidazole (MTZ), dimetridazole (DMZ) and 
      ronidazole (RNZ) residues in royal jelly was developed by high performance liquid 
      chromatography-tandem mass spectrometry (HPLC-MS/MS). After samples were 
      dissolved in sodium hydroxide solution to disassociate target analytes from 
      matrix, liquid-liquid extraction methods by ethyl acetate solvent were used. 
      Matrix effects were minimized and good quantitation results were obtained by 
      using highly-selective reaction monitoring (H-SRM) technology when deuterated 
      dimetridazole (dimetridazole-D3) was selected as internal standard. Limits of 
      detection (LODs) were 1.0 microg/kg for DMZ, 0.5 microg/kg for MTZ and RNZ (S/N > 
      5). Limits of quantitation (LOQs) were 2.0 microg/kg for DMZ, 1.0 microg/kg for 
      MTZ and RNZ (S/N > 10). The linear ranges were 2.0 - 200 microg/L for all target 
      analytes. Recoveries and relative standard deviations (RSDs) were in the ranges 
      of 96.6% - 110.6% and 2.1% -7.4%, respectively. This method is suitable for 
      statutory residue testing in the National Residue Surveillance Plan in China and 
      meets the requirement for export.
FAU - Ding, Tao
AU  - Ding T
AD  - National Honey Reference Laboratory, Animal, Plant and Food Inspection Center 
      (APFIC) of Jiangsu Entry-Exit Inspection and Quarantine Bureau, Nanjing 210001, 
      China. dingt@jsciq.gov.cn
FAU - Xu, Jinzhong
AU  - Xu J
FAU - Shen, Chongyu
AU  - Shen C
FAU - Jiang, Yuan
AU  - Jiang Y
FAU - Chen, Huilan
AU  - Chen H
FAU - Wu, Bin
AU  - Wu B
FAU - Zhao, Zengyun
AU  - Zhao Z
FAU - Li, Gonghai
AU  - Li G
FAU - Zhang, Jing
AU  - Zhang J
FAU - Liu, Fei
AU  - Liu F
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Fatty Acids)
RN  - 0 (Nitroimidazoles)
RN  - 045BU63E23 (Ipronidazole)
RN  - 140QMO216E (Metronidazole)
RN  - E01R4M1063 (Ronidazole)
RN  - K59P7XNB8X (Dimetridazole)
RN  - L497I37F0C (royal jelly)
SB  - IM
MH  - China
MH  - Dimetridazole/*analysis
MH  - Fatty Acids/*chemistry
MH  - Ipronidazole/analysis
MH  - Limit of Detection
MH  - Metronidazole/*analysis
MH  - Nitroimidazoles/*analysis
MH  - Reference Standards
MH  - Ronidazole/*analysis
MH  - Tandem Mass Spectrometry/*methods
EDAT- 2006/10/05 09:00
MHDA- 2010/07/08 06:00
CRDT- 2006/10/05 09:00
PHST- 2006/10/05 09:00 [pubmed]
PHST- 2010/07/08 06:00 [medline]
PHST- 2006/10/05 09:00 [entrez]
PST - ppublish
SO  - Se Pu. 2006 Jul;24(4):331-4.