PMID- 17027368 OWN - NLM STAT- MEDLINE DCOM- 20061109 LR - 20220419 IS - 1556-5653 (Electronic) IS - 0015-0282 (Linking) VI - 86 IP - 4 DP - 2006 Oct TI - Infertility in a man with oligoasthenoteratozoospermia associated with nonrobertsonian translocation t(9;15)(p10;q10). PG - 1001.e7-9 AB - OBJECTIVE: To analyze an unusual nonrobertsonian translocation t(9;15)(p10;q10) found in an infertile man with oligoasthenoteratozoospermia who had a normal phenotype. DESIGN: Case report with a review of scientific literature. SETTING: Academic research environment. PATIENT(S): Infertile man with oligoasthenoteratozoospermia but otherwise apparently healthy. INTERVENTION(S): Peripheral blood lymphocytes were obtained for karyotyping, and metaphases were studied by the GBG fluorescence in situ hybridization (FISH) procedure. MAIN OUTCOME MEASURE(S): Physical examination, semen analysis, GBG banding, and FISH procedure. RESULT(S): The semen analysis revealed oligoasthenoteratozoospermia. The lymphocytic karyotype detected a translocation t(9;15)(p10;q10), and FISH procedure showed that the derived chromosome had a chromosome 15 centromere. CONCLUSION(S): The association of unusual translocation with male factor infertility was described. To our knowledge no such association has been described previously in men whose clinical manifestation is only infertility. FAU - Aydos, Sena Erdogan AU - Aydos SE AD - Medico-Social Center, Cebeci Hospital, Ankara University School of Medicine, Ankara, Turkey. saydos@gmail.com FAU - Tukun, Ajlan AU - Tukun A LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Fertil Steril JT - Fertility and sterility JID - 0372772 SB - IM MH - Adult MH - Chromosomes, Human, Pair 1/*genetics MH - Chromosomes, Human, Pair 10/*genetics MH - Chromosomes, Human, Pair 15/*genetics MH - Chromosomes, Human, Pair 9/*genetics MH - Genetic Predisposition to Disease/genetics MH - Humans MH - Infertility, Male/genetics MH - Male MH - Oligospermia/*genetics MH - Spermatogenesis/*genetics MH - Translocation, Genetic/*genetics EDAT- 2006/10/10 09:00 MHDA- 2006/11/11 09:00 CRDT- 2006/10/10 09:00 PHST- 2005/09/18 00:00 [received] PHST- 2006/02/22 00:00 [revised] PHST- 2006/02/22 00:00 [accepted] PHST- 2006/10/10 09:00 [pubmed] PHST- 2006/11/11 09:00 [medline] PHST- 2006/10/10 09:00 [entrez] AID - S0015-0282(06)01285-4 [pii] AID - 10.1016/j.fertnstert.2006.02.124 [doi] PST - ppublish SO - Fertil Steril. 2006 Oct;86(4):1001.e7-9. doi: 10.1016/j.fertnstert.2006.02.124.