PMID- 17034701
OWN - NLM
STAT- MEDLINE
DCOM- 20061211
LR  - 20061012
IS  - 0049-4755 (Print)
IS  - 0049-4755 (Linking)
VI  - 36
IP  - 4
DP  - 2006 Oct
TI  - Hepatic histopathological findings in HIV patients at postmortem in Jos 
      university teaching hospital, Nigeria.
PG  - 228-31
AB  - Multi-organ involvement by opportunistic infections and neoplasms is the major 
      cause of morbidity and mortality in people living with HIV/AIDS. We determined 
      the spectrum/frequency of hepatic histopathological lesions in a prospective 
      study of postmortem liver biopsies from 100 patients (50 females and 50 males, 
      age range 18-55 years) who died from HIV/AIDS in Jos university teaching 
      hospital, Nigeria. The majority of the patients, 65 (65%), had clinical 
      tuberculosis. Granulomatous hepatitis, chronic hepatitis, non-specific reactive 
      hepatitis (NSRH) and steatosis were the commonest hepatic histopathologic lesions 
      occurring in 34, 20,15 and 12% of patients, respectively. Seven (7%) had normal 
      histological features. This study shows that the liver is affected in HIV/AIDS as 
      reported elsewhere in the world. Therefore, liver biopsy in HIV patients may be 
      helpful in the management of these patients.
FAU - Echejoh, Godwins O
AU  - Echejoh GO
AD  - Department of Anatomic Pathology, Jos University Teaching Hospital, Jos, Plateau 
      State, Nigeria. ogechejoh@yahoo.com
FAU - Mandong, Barnabas M
AU  - Mandong BM
FAU - Tanko, Matthew N
AU  - Tanko MN
FAU - Manasseh, Agabus N
AU  - Manasseh AN
FAU - Okeke, Edith N
AU  - Okeke EN
FAU - Agaba, Emmanuel I
AU  - Agaba EI
LA  - eng
PT  - Journal Article
PL  - England
TA  - Trop Doct
JT  - Tropical doctor
JID - 1301706
SB  - IM
MH  - AIDS-Related Opportunistic Infections/diagnosis/pathology
MH  - Adolescent
MH  - Adult
MH  - *Autopsy
MH  - Biopsy
MH  - Female
MH  - HIV Infections/*complications/pathology
MH  - *Hospitals, Teaching
MH  - *Hospitals, University
MH  - Humans
MH  - Liver
MH  - Liver Diseases/diagnosis/*pathology
MH  - Male
MH  - Middle Aged
EDAT- 2006/10/13 09:00
MHDA- 2006/12/12 09:00
CRDT- 2006/10/13 09:00
PHST- 2006/10/13 09:00 [pubmed]
PHST- 2006/12/12 09:00 [medline]
PHST- 2006/10/13 09:00 [entrez]
AID - 10.1258/004947506778604832 [doi]
PST - ppublish
SO  - Trop Doct. 2006 Oct;36(4):228-31. doi: 10.1258/004947506778604832.