PMID- 17044825
OWN - NLM
STAT- MEDLINE
DCOM- 20070412
LR  - 20161124
IS  - 0013-9580 (Print)
IS  - 0013-9580 (Linking)
VI  - 47 Suppl 1
DP  - 2006
TI  - In nonconvulsive status epilepticus (NCSE), treat to burst-suppression: pro and 
      con.
PG  - 41-5
AB  - Dr. Jordan (PRO) argues that when refractory NCSE is combined with acute brain 
      injury, it produces synergistically compounded brain damage that is time 
      dependent. Treating to EEG burst-suppression is the most rapid and effective 
      method for stopping NCSE. The risks of burst-suppression are common to many 
      intensive care interventions and can be minimized with expert management. Dr. 
      Hirsch (CON) argues that treating with coma-inducing medication is highly risky 
      and has a high mortality rate, often due to iatrogenic complications. It remains 
      unclear if nonconvulsive seizures cause permanent neuronal injury. Nonconvulsive 
      seizures should be diagnosed and treated as quickly as possible,but with 
      non-coma-inducing treatments in most cases [corrected]
FAU - Jordan, Kenneth G
AU  - Jordan KG
AD  - Jordan NeuroScience, Inc., San Bernardino, California 92404, USA. 
      info@jordaneuro.com
FAU - Hirsch, Lawrence J
AU  - Hirsch LJ
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Epilepsia
JT  - Epilepsia
JID - 2983306R
RN  - 0 (Anticonvulsants)
SB  - IM
EIN - Epilepsia. 2006 Dec;47(12):2211
MH  - Acidosis/chemically induced/mortality
MH  - Adolescent
MH  - Anticonvulsants/adverse effects/pharmacology/*therapeutic use
MH  - Brain/physiopathology
MH  - Brain Injuries/*complications/diagnostic imaging/physiopathology
MH  - Coma/chemically induced/mortality
MH  - Electroencephalography/*drug effects/statistics & numerical data
MH  - Humans
MH  - Male
MH  - Prognosis
MH  - Recurrence
MH  - Status Epilepticus/*drug therapy/*etiology/physiopathology
MH  - Tomography, X-Ray Computed
EDAT- 2006/10/19 09:00
MHDA- 2007/04/14 09:00
CRDT- 2006/10/19 09:00
PHST- 2006/10/19 09:00 [pubmed]
PHST- 2007/04/14 09:00 [medline]
PHST- 2006/10/19 09:00 [entrez]
AID - EPI659 [pii]
AID - 10.1111/j.1528-1167.2006.00659.x [doi]
PST - ppublish
SO  - Epilepsia. 2006;47 Suppl 1:41-5. doi: 10.1111/j.1528-1167.2006.00659.x.