PMID- 17048090
OWN - NLM
STAT- MEDLINE
DCOM- 20070410
LR  - 20081121
IS  - 0006-2928 (Print)
IS  - 0006-2928 (Linking)
VI  - 44
IP  - 9-10
DP  - 2006 Oct
TI  - Genetic variation of Chinese PRRSV strains based on ORF5 sequence.
PG  - 425-35
AB  - Thirteen isolates of porcine reproductive and respiratory syndrome virus (PRRSV) 
      from different provinces of China were studied and compared with several PRRSV 
      isolates from other countries. Phylogenetic analysis shows that all Chinese 
      isolates of PRRSV in this study belong to the American genotype, except for one 
      strain, B13, which clustered as a European genotype. Sequence analysis revealed 
      that PRRSV Chinese isolates of the American genotype were highly similar in the 
      ORF5 sequence and could be classified into two subclades. One contains PRRSV 
      isolates that are more closely related to the American vaccine strain MLV Resp 
      and its parent strain VR-2332, and the other contains ones only distantly related 
      to them. Within the Chinese isolates slight genetic variation occurred, and some 
      strains may originate directly from the vaccine virus.
FAU - Chen, Jian
AU  - Chen J
AD  - College of Life Sciences, Zhejiang University, Hangzhou, PR China.
FAU - Liu, Tao
AU  - Liu T
FAU - Zhu, Cheng-Gang
AU  - Zhu CG
FAU - Jin, Yong-Feng
AU  - Jin YF
FAU - Zhang, Yao-Zhou
AU  - Zhang YZ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20060919
PL  - United States
TA  - Biochem Genet
JT  - Biochemical genetics
JID - 0126611
RN  - 0 (DNA Primers)
SB  - IM
MH  - Amino Acid Sequence
MH  - Base Sequence
MH  - DNA Primers
MH  - Genes, Viral
MH  - *Genetic Variation
MH  - Genotype
MH  - Molecular Sequence Data
MH  - Open Reading Frames
MH  - Phylogeny
MH  - Porcine respiratory and reproductive syndrome virus/*genetics
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Sequence Homology, Amino Acid
EDAT- 2006/10/19 09:00
MHDA- 2007/04/11 09:00
CRDT- 2006/10/19 09:00
PHST- 2005/11/03 00:00 [received]
PHST- 2006/02/21 00:00 [accepted]
PHST- 2006/10/19 09:00 [pubmed]
PHST- 2007/04/11 09:00 [medline]
PHST- 2006/10/19 09:00 [entrez]
AID - 10.1007/s10528-006-9039-9 [doi]
PST - ppublish
SO  - Biochem Genet. 2006 Oct;44(9-10):425-35. doi: 10.1007/s10528-006-9039-9. Epub 
      2006 Sep 19.