PMID- 17070818
OWN - NLM
STAT- MEDLINE
DCOM- 20070306
LR  - 20161124
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 1138
IP  - 1-2
DP  - 2007 Jan 5
TI  - Simultaneous determination of the endocrine disrupting compounds nonylphenol, 
      nonylphenol ethoxylates, triclosan and bisphenol A in wastewater and sewage 
      sludge by gas chromatography-mass spectrometry.
PG  - 32-41
AB  - An integrated analytical method for the simultaneous determination of 
      4-n-nonylphenol (4-n-NP), nonylphenol monoethoxylate (NP1EO), nonylphenol 
      diethoxylate (NP2EO), bisphenol A (BPA) and triclosan (TCS) in wastewater 
      (dissolved and particulate phase) and sewage sludge was developed based on gas 
      chromatography-mass spectrometry. Chromatographic analysis was achieved after 
      derivatization with bis(trimethylsilyl)trifluoroacetamide (BSTFA). Extraction 
      from water samples was performed by solid-phase extraction (SPE). The 
      optimization of SPE procedure included the type of sorbent and the type of the 
      organic solvent used for the elution. Referred to solid samples, the target 
      compounds were extracted by sonication. In this case the optimization of the 
      extraction procedure included the variation of the amount of the extracted 
      biomass, the duration and the temperature of sonication and the type of the 
      extraction organic solvent. The developed extraction procedures resulted in good 
      repeatability and reproducibility with relative standard deviations (RSDs) less 
      than 13% for all the tested compounds for both types of samples. Satisfactory 
      recoveries were obtained (>60%) for all the compounds in both liquid and solid 
      samples, except for 4-n-NP, which gave recoveries up to 35% in wastewater samples 
      and up to 63% in sludge samples. The limits of detection (LODs) of the target 
      compounds varied from 0.03 (4-n-NP) to 0.41 microg l(-1) (NP2EO) and from 0.04 
      (4-n-NP) to 0.96 microg kg(-1) (NP2EO) for liquid and solid samples, 
      respectively. The developed methods were successfully applied to the analysis of 
      the target compounds in real samples.
FAU - Gatidou, Georgia
AU  - Gatidou G
AD  - Laboratory of Analytical Chemistry, Department of Chemistry, University of 
      Athens, Panepistimioupolis Zografou, 15771 Athens, Greece.
FAU - Thomaidis, Nikolaos S
AU  - Thomaidis NS
FAU - Stasinakis, Athanasios S
AU  - Stasinakis AS
FAU - Lekkas, Themistokles D
AU  - Lekkas TD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20061030
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Endocrine Disruptors)
RN  - 0 (Phenols)
RN  - 0 (Sewage)
RN  - 0 (Water Pollutants, Chemical)
RN  - 4NM5039Y5X (Triclosan)
RN  - 79F6A2ILP5 (nonylphenol)
SB  - IM
MH  - Endocrine Disruptors/*analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Phenols/analysis
MH  - Reproducibility of Results
MH  - Sewage/*analysis/chemistry
MH  - Solid Phase Extraction
MH  - Triclosan/analysis
MH  - Water Pollutants, Chemical/analysis
EDAT- 2006/10/31 09:00
MHDA- 2007/03/07 09:00
CRDT- 2006/10/31 09:00
PHST- 2006/07/30 00:00 [received]
PHST- 2006/10/17 00:00 [revised]
PHST- 2006/10/18 00:00 [accepted]
PHST- 2006/10/31 09:00 [pubmed]
PHST- 2007/03/07 09:00 [medline]
PHST- 2006/10/31 09:00 [entrez]
AID - S0021-9673(06)02013-9 [pii]
AID - 10.1016/j.chroma.2006.10.037 [doi]
PST - ppublish
SO  - J Chromatogr A. 2007 Jan 5;1138(1-2):32-41. doi: 10.1016/j.chroma.2006.10.037. 
      Epub 2006 Oct 30.