PMID- 17092866
OWN - NLM
STAT- MEDLINE
DCOM- 20070109
LR  - 20111117
IS  - 0301-4460 (Print)
IS  - 0301-4460 (Linking)
VI  - 33
IP  - 3
DP  - 2006 May-Jun
TI  - HLA-DRB1 frequencies of the Comorian population and their genetic affinities with 
      Sub-Saharan African and Indian Oceanian populations.
PG  - 265-78
AB  - BACKGROUND: Ethnic-historic sources have considered the Comorian population to be 
      the result of an amalgamation of African, Arabian and Southeast Asian groups. 
      AIM: This study seeks to determine the genetic relationships and contributions 
      from Sub-Saharan Africa and Indian Oceania and to reconstruct past migration 
      events. SUBJECTS AND METHODS: The human leukocyte antigen (HLA) polymorphism of a 
      Comorian population was described and analysed. RESULTS: Genetic distances and 
      multidimensional scaling analyses showed complex patterns of genetic 
      differentiation in the Indian Oceanian area as a result of continuous gene flow 
      occurring within the past approximately 2500 years. Nevertheless, the Comorian 
      genetic pool appears to be a mix of Bantu-speaking and Arab populations as 
      testified to by admixture estimations of almost 50-60% and 27-33%, respectively. 
      CONCLUSION: The Comorian population may represent the eastern limit of the recent 
      and massive eastward Bantu expansion. In contrast to the population from 
      Madagascar (Merina), only a restricted influence of Austronesian populations was 
      found.
FAU - Gibert, M
AU  - Gibert M
AD  - Centre d'Anthropologie, UMR 8555, CNRS, Toulouse, France. gibert@cict.fr
FAU - Touinssi, M
AU  - Touinssi M
FAU - Reviron, D
AU  - Reviron D
FAU - Mercier, P
AU  - Mercier P
FAU - Boetsch, G
AU  - Boetsch G
FAU - Chiaroni, J
AU  - Chiaroni J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Ann Hum Biol
JT  - Annals of human biology
JID - 0404024
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - Africa South of the Sahara
MH  - *Gene Frequency
MH  - *Genetics, Population
MH  - HLA-DR Antigens/*genetics
MH  - HLA-DRB1 Chains
MH  - Humans
MH  - Indian Ocean Islands
MH  - Polymorphism, Genetic
EDAT- 2006/11/10 09:00
MHDA- 2007/01/11 09:00
CRDT- 2006/11/10 09:00
PHST- 2006/11/10 09:00 [pubmed]
PHST- 2007/01/11 09:00 [medline]
PHST- 2006/11/10 09:00 [entrez]
AID - W6367X2Q9T335823 [pii]
AID - 10.1080/03014460600578599 [doi]
PST - ppublish
SO  - Ann Hum Biol. 2006 May-Jun;33(3):265-78. doi: 10.1080/03014460600578599.