PMID- 17094031
OWN - NLM
STAT- MEDLINE
DCOM- 20070126
LR  - 20240322
IS  - 1090-0586 (Print)
IS  - 1573-3270 (Electronic)
IS  - 1090-0586 (Linking)
VI  - 31
IP  - 4
DP  - 2006 Dec
TI  - Cardiovascular correlates of motor vehicle accident related posttraumatic stress 
      disorder and its successful treatment.
PG  - 315-30
AB  - Persons with posttraumatic stress disorder (PTSD) have been shown to display 
      elevated baseline cardiovascular activity and a heightened physiological 
      reactivity to trauma-related stimuli. Study 1 examined differences in baseline 
      heart rate (HR) and HR reactivity in 68 survivors of motor vehicle accidents 
      (MVAs) and healthy controls without MVA. MVA survivors with PTSD (n=26), 
      subsyndromal PTSD (n=22), traumatized controls without PTSD (non-PTSD with MVA, 
      n=20) and healthy controls without MVA (HC, n=27) underwent measurement of HR 
      during baseline and exposure to a neutral, positive, negative, and trauma-related 
      picture. PTSD patients showed elevated baseline HR and increased HR reactivity 
      only during exposure to the trauma-related picture. Study 2 investigated whether 
      the elevated physiological responses observed in Study 1 normalized after 
      cognitive behavioral therapy (CBT). We conducted a randomized, controlled 
      treatment trial comparing CBT (n=17) to a Wait-list condition (WLC, n=18). 
      Results showed a greater decrease in HR reactivity for CBT than for WLC. The 
      change in HR reactivity was associated with clinical improvement.
FAU - Rabe, Sirko
AU  - Rabe S
AD  - Department of Psychology, Dresden University of Technology, Dresden, Germany. 
      rabe@biopsych.tu-dresden.de
FAU - Dorfel, Denise
AU  - Dorfel D
FAU - Zollner, Tanja
AU  - Zollner T
FAU - Maercker, Andreas
AU  - Maercker A
FAU - Karl, Anke
AU  - Karl A
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20061109
PL  - Germany
TA  - Appl Psychophysiol Biofeedback
JT  - Applied psychophysiology and biofeedback
JID - 9712383
SB  - IM
MH  - *Accidents, Traffic
MH  - Adult
MH  - Affect/physiology
MH  - Cognitive Behavioral Therapy
MH  - Electrocardiography
MH  - Female
MH  - Heart Rate/physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Photic Stimulation
MH  - Psychiatric Status Rating Scales
MH  - Psychometrics
MH  - Stress Disorders, Post-Traumatic/diagnosis/*physiopathology/*therapy
MH  - Treatment Outcome
PMC - PMC1705541
EDAT- 2006/11/10 09:00
MHDA- 2007/01/27 09:00
PMCR- 2006/12/18
CRDT- 2006/11/10 09:00
PHST- 2006/03/27 00:00 [received]
PHST- 2006/10/02 00:00 [accepted]
PHST- 2006/11/10 09:00 [pubmed]
PHST- 2007/01/27 09:00 [medline]
PHST- 2006/11/10 09:00 [entrez]
PHST- 2006/12/18 00:00 [pmc-release]
AID - 9027 [pii]
AID - 10.1007/s10484-006-9027-1 [doi]
PST - ppublish
SO  - Appl Psychophysiol Biofeedback. 2006 Dec;31(4):315-30. doi: 
      10.1007/s10484-006-9027-1. Epub 2006 Nov 9.