PMID- 17097570
OWN - NLM
STAT- MEDLINE
DCOM- 20070206
LR  - 20161124
IS  - 1553-4650 (Print)
IS  - 1553-4650 (Linking)
VI  - 13
IP  - 6
DP  - 2006 Nov-Dec
TI  - A new technique to obtain endometrial directed biopsy during sonohysterography: 
      the NiGo device.
PG  - 505-9
AB  - The primary goal of the clinical evaluation of abnormal uterine bleeding is to 
      establish a specific diagnosis in the most efficient and least invasive manner 
      possible. Hysteroscopy (HS) allows physicians to obtain directed biopsy in 
      addition to direct visualization of the uterine cavity and lesions, but often 
      requires ambulatory surgery centers and some anesthesia, or can potentially 
      result in significant patient discomfort. Sonohysterography (SHG) is less 
      invasive than HS but does not allow a histologic sample. A new technique, called 
      the Nicoletti-Gorlero (NiGo) device, was developed and evaluated to obtain 
      histologic results during SHG. This study is a prospective, observational 
      evaluation between the NiGo device technique and standard HS to obtain 
      endometrial samples. The NiGo device was used to obtain an endometrial sample 
      during SHG in 18 women. In a subsequent session, HS was performed to verify the 
      results. From January 2005 through November 2005 both procedures (SHG + biopsy 
      and HS) were performed on 18 patients. The SHG procedures using the NiGo forcep 
      were performed successfully on 15 out of 18 women, and the endometrial sample was 
      obtained in 14 out of 15 patients. In one patient, the endometrial biopsy 
      obtained provided too little tissue to accomplish histologic evaluation. All 13 
      pathologic results obtained with the NiGo device were identical with those 
      subsequently obtained with HS. The office-based HS procedure was not successful 
      in two women; in these women, an HS procedure performed in the operating room was 
      necessary. The NiGo device technique allows the physician to obtain 
      sonographic-guided biopsies of the entire endometrium during SHG. The technique 
      is less invasive compared with HS. In our small series, there were no 
      complications during the procedure.
FAU - Nicoletti, Luca
AU  - Nicoletti L
AD  - Department of Women and Children, Division of Obstetrics and Gynecology, Imperia 
      Hospital, Imperia, Italy.
FAU - Gorlero, Franco
AU  - Gorlero F
FAU - Lijoi, Davide
AU  - Lijoi D
FAU - Nicoletti, Annamaria
AU  - Nicoletti A
FAU - Lorenzi, Paola
AU  - Lorenzi P
FAU - Ragni, Nicola
AU  - Ragni N
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Minim Invasive Gynecol
JT  - Journal of minimally invasive gynecology
JID - 101235322
SB  - IM
MH  - Aged
MH  - Biopsy/*instrumentation
MH  - Endometrium/diagnostic imaging/*pathology
MH  - Equipment Design
MH  - Female
MH  - Humans
MH  - *Hysteroscopy
MH  - Middle Aged
MH  - Prospective Studies
MH  - Ultrasonography
MH  - Uterine Hemorrhage/diagnostic imaging/*etiology/pathology
EDAT- 2006/11/14 09:00
MHDA- 2007/02/07 09:00
CRDT- 2006/11/14 09:00
PHST- 2006/07/13 00:00 [received]
PHST- 2006/08/04 00:00 [revised]
PHST- 2006/08/04 00:00 [accepted]
PHST- 2006/11/14 09:00 [pubmed]
PHST- 2007/02/07 09:00 [medline]
PHST- 2006/11/14 09:00 [entrez]
AID - S1553-4650(06)00395-5 [pii]
AID - 10.1016/j.jmig.2006.08.003 [doi]
PST - ppublish
SO  - J Minim Invasive Gynecol. 2006 Nov-Dec;13(6):505-9. doi: 
      10.1016/j.jmig.2006.08.003.