PMID- 17098415 OWN - NLM STAT- MEDLINE DCOM- 20070726 LR - 20161124 IS - 0956-5663 (Print) IS - 0956-5663 (Linking) VI - 22 IP - 12 DP - 2007 Jun 15 TI - Potassium selective chemically modified field effect transistors based on AlGaN/GaN two-dimensional electron gas heterostructures. PG - 2796-801 AB - We investigate the use of the AlGaN/GaN high electron mobility transistor (HEMT) as a novel transducer for the development of ion-selective chemically modified HEMT sensors (ChemHEMTs). For this, polyvinyl chloride (PVC) membrane doped with ion-selective ionophores is deposited onto the area of the gate for the chemical recognition step, while the AlGaN/GaN HEMT is used as the transducer. In particular, the use of a valinocycin doped membrane with thickness of 50 microm generates a sensor with excellent analytical characteristics for the monitoring of K(+). The K(+)-ChemHEMT has sensitivity of 52.4 mV/pK(+)in the linear range of 10(-5) to 10(-2)M, while the detection limit is in the order of 3.1 x 10(-6)M. Also, the sensor shows selectivity similar to valinomycin-based ISEs, while the signal stability over time and the measurement to measurement reproducibility are very good. FAU - Alifragis, Y AU - Alifragis Y AD - Laboratory of Analytical Chemistry, Department of Chemistry, University of Crete, Voutes, PO Box 2208, 71003 Iraklion-Crete, Greece. FAU - Volosirakis, A AU - Volosirakis A FAU - Chaniotakis, N A AU - Chaniotakis NA FAU - Konstantinidis, G AU - Konstantinidis G FAU - Adikimenakis, A AU - Adikimenakis A FAU - Georgakilas, A AU - Georgakilas A LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20061113 PL - England TA - Biosens Bioelectron JT - Biosensors & bioelectronics JID - 9001289 RN - 0 (Aluminum Compounds) RN - 0 (aluminum gallium nitride) RN - 1R9CC3P9VL (gallium nitride) RN - CH46OC8YV4 (Gallium) RN - RWP5GA015D (Potassium) SB - IM MH - Aluminum Compounds/*chemistry MH - Biosensing Techniques/*instrumentation/methods MH - Electrons MH - Gallium/*chemistry MH - Potassium/*analysis MH - Potentiometry MH - *Transistors, Electronic EDAT- 2006/11/14 09:00 MHDA- 2007/07/27 09:00 CRDT- 2006/11/14 09:00 PHST- 2006/06/30 00:00 [received] PHST- 2006/09/26 00:00 [revised] PHST- 2006/10/03 00:00 [accepted] PHST- 2006/11/14 09:00 [pubmed] PHST- 2007/07/27 09:00 [medline] PHST- 2006/11/14 09:00 [entrez] AID - S0956-5663(06)00487-8 [pii] AID - 10.1016/j.bios.2006.10.010 [doi] PST - ppublish SO - Biosens Bioelectron. 2007 Jun 15;22(12):2796-801. doi: 10.1016/j.bios.2006.10.010. Epub 2006 Nov 13.