PMID- 17098717
OWN - NLM
STAT- MEDLINE
DCOM- 20090417
LR  - 20190922
IS  - 0253-9772 (Print)
IS  - 0253-9772 (Linking)
VI  - 28
IP  - 11
DP  - 2006 Nov
TI  - [Progress in the study of KRAB zinc finger protein].
PG  - 1451-6
AB  - The zinc finger proteins containing the Kruppel-associated box domain (KRAB) 
      constitute the largest single family of transcriptional regulators in mammals. 
      Many genes encoding members of this family are arranged in clusters. 
      KRAB-containing proteins are characterized by the presence of 4 and over 30 C2H2 
      zinc-finger motifs and a KRAB domain near the amino terminus of the protein. KRAB 
      domain behaving as a protein-protein interaction domain could bind to corepressor 
      proteins and/or transcription factors, and that the KRAB-containing proteins 
      could act as a repressor or corepressor and play a key role in transcriptional 
      repression. Members of the family are involved in embryonic development, cell 
      differentiation, cell proliferation, apoptosis, neoplastic transformation and 
      cell cycle regulation.
FAU - Tian, Chun-Yan
AU  - Tian CY
AD  - Laboratory of Systems Biology, Institute of Radiation Medicine, Beijing 100850, 
      China.
FAU - Zhang, Ling-Qiang
AU  - Zhang LQ
FAU - He, Fu-Chu
AU  - He FC
LA  - chi
PT  - Journal Article
PT  - Review
PL  - China
TA  - Yi Chuan
JT  - Yi chuan = Hereditas
JID - 9436478
RN  - 0 (Kruppel-Like Transcription Factors)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Cell Physiological Phenomena
MH  - Chromosomes, Human/metabolism
MH  - Humans
MH  - Kruppel-Like Transcription Factors/*chemistry/genetics/*metabolism
MH  - Molecular Sequence Data
MH  - Protein Structure, Tertiary
MH  - *Zinc Fingers
RF  - 34
EDAT- 2006/11/14 09:00
MHDA- 2009/04/18 09:00
CRDT- 2006/11/14 09:00
PHST- 2006/11/14 09:00 [pubmed]
PHST- 2009/04/18 09:00 [medline]
PHST- 2006/11/14 09:00 [entrez]
AID - 0253-9772(2006)11-1451-06 [pii]
AID - 10.1360/yc-006-1451 [doi]
PST - ppublish
SO  - Yi Chuan. 2006 Nov;28(11):1451-6. doi: 10.1360/yc-006-1451.