PMID- 17100526 OWN - NLM STAT- MEDLINE DCOM- 20061228 LR - 20220317 IS - 0021-843X (Print) IS - 0021-843X (Linking) VI - 115 IP - 4 DP - 2006 Nov TI - Regional brain electrical activity in posttraumatic stress disorder after motor vehicle accident. PG - 687-98 AB - This study examined whether patients with posttraumatic stress disorder (PTSD) related to motor vehicle accidents (MVAs) would show an abnormal pattern of electroencephalographic (EEG) alpha asymmetries, which has been proposed for particular types of anxiety. Patients with PTSD (n = 22) or subsyndromal PTSD (n = 21), traumatized controls without PTSD (non-PTSD with MVA; n = 21), and healthy controls without MVA (n = 23) underwent measurement of EEG activity during baseline and exposure to a neutral, a positive, a negative, and an accident-related picture. Differences in brain asymmetry between groups were observed only during exposure to trauma-related material. PTSD and subsyndromal PTSD patients showed a pattern of enhanced right anterior and posterior activation, whereas non-PTSD with MVA participants showed the opposite pattern. Furthermore, posterior asymmetry in nontraumatized healthy controls varied with gender, with female participants showing a pattern of higher right posterior activation. The results support the hypothesis that symptomatic MVA survivors are characterized by a pattern of right hemisphere activation that is associated with anxious arousal and symptoms of PTSD during processing of trauma-specific information. CI - (c) 2006 APA, all rights reserved. FAU - Rabe, Sirko AU - Rabe S AD - Department of Biopsychology, Dresden University of Technology, Dresden, Germany. rabe@biopsych.tu-dresden.de FAU - Beauducel, Andre AU - Beauducel A FAU - Zollner, Tanja AU - Zollner T FAU - Maercker, Andreas AU - Maercker A FAU - Karl, Anke AU - Karl A LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Abnorm Psychol JT - Journal of abnormal psychology JID - 0034461 SB - IM MH - Accidents, Traffic/*statistics & numerical data MH - Adult MH - Affect MH - Alpha Rhythm MH - Brain/*physiopathology MH - *Electroencephalography MH - Female MH - Humans MH - Male MH - Motor Vehicles/*statistics & numerical data MH - Severity of Illness Index MH - Stress Disorders, Post-Traumatic/*diagnosis/*physiopathology/psychology EDAT- 2006/11/15 09:00 MHDA- 2006/12/29 09:00 CRDT- 2006/11/15 09:00 PHST- 2006/11/15 09:00 [pubmed] PHST- 2006/12/29 09:00 [medline] PHST- 2006/11/15 09:00 [entrez] AID - 2006-20696-004 [pii] AID - 10.1037/0021-843X.115.4.687 [doi] PST - ppublish SO - J Abnorm Psychol. 2006 Nov;115(4):687-98. doi: 10.1037/0021-843X.115.4.687.